Porcine circovirus type 2 (PCV2) vaccines in the context of current molecular epidemiology

AK Karuppannan, T Opriessnig - Viruses, 2017 - mdpi.com
Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and,
although small, it has the highest evolution rate among DNA viruses. Since the discovery of …

Porcine circovirus type 2 (PCV2): pathogenesis and interaction with the immune system

XJ Meng - Annu. Rev. Anim. Biosci., 2013 - annualreviews.org
Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus–
associated disease (PCVAD). The virus preferentially targets the lymphoid tissues, which …

Porcine circovirus 2 (PCV-2) genotype update and proposal of a new genotyping methodology

G Franzo, J Segalés - PloS one, 2018 - journals.plos.org
Porcine circovirus 2 (PCV-2) is one of the most widespread viral infections of swine, causing
a remarkable economic impact because of direct losses and indirect costs for its control. As …

Global molecular genetic analysis of porcine circovirus type 2 (PCV2) sequences confirms the presence of four main PCV2 genotypes and reveals a rapid increase of …

CT Xiao, PG Halbur… - Journal of General …, 2015 - microbiologyresearch.org
The oldest porcine circovirus type 2 (PCV2) sequence dates back to 1962 and is among
several hundreds of publicly available PCV2 sequences. Despite this resource, few studies …

Phylodynamic analysis of porcine circovirus type 2 reveals global waves of emerging genotypes and the circulation of recombinant forms

G Franzo, M Cortey, J Segalés, J Hughes… - Molecular phylogenetics …, 2016 - Elsevier
Since the first description of Porcine circovirus type 2 (PCV2), four genotypes (PCV2a,
PCV2b, PCV2c and PCV2d) have been recognized and three of them have been shown to …

Porcine circovirus 2 genotypes, immunity and vaccines: Multiple genotypes but one single serotype

G Franzo, J Segalés - Pathogens, 2020 - mdpi.com
Identified for the first time in the 1990s, Porcine circovirus 2 (PCV-2) should not be
considered an emerging virus anymore. Nevertheless, many aspects of its biology and …

Insights into the evolutionary history of an emerging livestock pathogen: porcine circovirus 2

C Firth, MA Charleston, S Duffy, B Shapiro… - Journal of …, 2009 - Am Soc Microbiol
ABSTRACT Porcine circovirus 2 (PCV2) is the primary etiological agent of postweaning
multisystemic wasting syndrome (PMWS), one of the most economically important emerging …

The natural history of porcine circovirus type 2: from an inoffensive virus to a devastating swine disease?

J Segalés, T Kekarainen, M Cortey - Veterinary microbiology, 2013 - Elsevier
The present review summarizes the current knowledge on the natural history of porcine
circovirus type 2 (PCV2) infection and its related diseases. The perception about PCV2 as a …

Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2)

NM Beach, XJ Meng - Virus research, 2012 - Elsevier
Porcine circovirus type 2 (PCV2) is the causative agent of an economically significant
collection of disease syndromes in pigs, now known as porcine circovirus associated …

PCV-2 genotype definition and nomenclature

J Segalés, A Olvera, L Grau-Roma… - The Veterinary …, 2008 - search.proquest.com
SIR,–To date, at least three different phylogenetic groups of porcine circovirus type 2 (PCV-
2) have been recognised (Gagnon and others 2007, Dupont and others 2008, Grau-Roma …