Skeletal muscle atrophy: From mechanisms to treatments

L Yin, N Li, W Jia, N Wang, M Liang, X Yang… - Pharmacological …, 2021 - Elsevier
Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

Muscle, bone, and fat crosstalk: the biological role of myokines, osteokines, and adipokines

B Kirk, J Feehan, G Lombardi, G Duque - Current osteoporosis reports, 2020 - Springer
Abstract Purpose of Review Skeletal muscle and bone are connected anatomically and
physiologically, and play a crucial role in human locomotion and metabolism. Historically …

Resistance exercise training as a primary countermeasure to age-related chronic disease

JC Mcleod, T Stokes, SM Phillips - Frontiers in physiology, 2019 - frontiersin.org
Age is a primary risk factor for a number of chronic diseases including mobility disability,
cardiovascular disease (CVD), type 2 diabetes (T2D), and cancer. Most physical activity …

Sarcopenia: etiology, nutritional approaches, and miRNAs

R Cannataro, L Carbone, JL Petro, E Cione… - International journal of …, 2021 - mdpi.com
Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically
affects the quality of life. Although there is a consensus that sarcopenia is a multifactorial …

Reduced physical activity in young and older adults: metabolic and musculoskeletal implications

KA Bowden Davies, S Pickles… - Therapeutic …, 2019 - journals.sagepub.com
Background: Although the health benefits of regular physical activity and exercise are well
established and have been incorporated into national public health recommendations, there …

Irisin ameliorates age‐associated sarcopenia and metabolic dysfunction

M Guo, J Yao, J Li, J Zhang, D Wang… - Journal of cachexia …, 2023 - Wiley Online Library
Background Age‐associated sarcopenia is characterized of progressed loss of skeletal
muscle power, mass, and function, which affects human physical activity and life quality …

Lactobacillus and Bifidobacterium Improves Physiological Function and Cognitive Ability in Aged Mice by the Regulation of Gut Microbiota

Y Ni, X Yang, L Zheng, Z Wang, L Wu… - Molecular Nutrition & …, 2019 - Wiley Online Library
Scope Age‐related degeneration is associated with imbalances of gut microbiota and its
related immune system, thus gut microbiota dysbiosis is considered to be a key target to …

Skeletal muscle oxidative stress and inflammation in aging: Focus on antioxidant and anti-inflammatory therapy

M Chen, Y Wang, S Deng, Z Lian, K Yu - Frontiers in Cell and …, 2022 - frontiersin.org
With aging, the progressive loss of skeletal muscle will have negative effect on multiple
physiological parameters, such as exercise, respiration, thermoregulation, and metabolic …

Social isolation, loneliness and physical performance in older-adults: fixed effects analyses of a cohort study

KEJ Philip, MI Polkey, NS Hopkinson, A Steptoe… - Scientific reports, 2020 - nature.com
Isolation and loneliness are related to various aspects of health. Physical performance is a
central component of health. However, its relationship with isolation and loneliness is not …

Current progress in tendon and ligament tissue engineering

WL Lim, LL Liau, MH Ng, SR Chowdhury… - Tissue engineering and …, 2019 - Springer
Background: Tendon and ligament injuries accounted for 30% of all musculoskeletal
consultations with 4 million new incidences worldwide each year and thus imposed a …