Immunohistochemistry represents an indispensable complement to an epidemiology and
morphology-driven approach to tumor diagnosis and site of origin assignment. This review …

Context.—Current 2013 World Health Organization classification of tumors of soft tissue
arranges these tumors into 12 groups according to their histogenesis. Tumor behavior is …

Malignant renal tumors account for 7% of childhood cancers, and Wilms tumors are by far
the most common—but not in older children and adolescents. Among individuals in the latter …

Desmoplastic small round cell tumor (DSRCT) is a soft tissue sarcoma of mesenchymal cell
origin that typically presents with multiple intra-abdominal tumors and exhibits a multi …

Renal tumors comprise approximately 7% of all malignant pediatric tumors. This is a highly
heterogeneous group of tumors, each with its own therapeutic management, outcome, and …

The diagnosis of small round cell tumors always has been extremely difficult, and our current
classification systems continue to evolve. Since its initial discovery by Dr James Ewing, the …

Making a correct diagnosis when dealing with a small round blue cell tumor (SRBCT) of
children and adolescents may be relatively straightforward if the tumor arises in the typical …

Desmoplastic small round cell tumor (DSRCT) is an aggressive small round cell neoplasm
which predominantly occurs intra-abdominally in adolescents and young adults with a male …

Primary mesenchymal tumours of the pleura are uncommon and can be diagnostically
challenging due to their overlapping histopathologic and immunophenotypic features …

Context.—Bone and soft tissue tumors are heterogeneous, diagnostically challenging, and
often defined by gene fusions. Objective.—To present our experience using a custom 34 …