Manipulation and motion of organelles and single molecules in living cells

K Norregaard, R Metzler, CM Ritter… - Chemical …, 2017 - ACS Publications
The biomolecule is among the most important building blocks of biological systems, and a
full understanding of its function forms the scaffold for describing the mechanisms of higher …

The cell as matter: Connecting molecular biology to cellular functions

Y Li, W Tang, M Guo - Matter, 2021 - cell.com
Viewing cells as matter to understand the intracellular biomolecular processes and
multicellular tissue behavior represents an emerging research area at the interface of …

Activity-driven fluctuations in living cells

É Fodor, M Guo, NS Gov, P Visco, DA Weitz… - Europhysics …, 2015 - iopscience.iop.org
We propose a model for the dynamics of a probe embedded in a living cell, where both
thermal fluctuations and nonequilibrium activity coexist. The model is based on a confining …

Feedback-tracking microrheology in living cells

K Nishizawa, M Bremerich, H Ayade, CF Schmidt… - Science …, 2017 - science.org
Living cells are composed of active materials, in which forces are generated by the energy
derived from metabolism. Forces and structures self-organize to shape the cell and drive its …

Quantitative cell biology of tip growth in moss

JP Bibeau, G Galotto, M Wu, E Tüzel, L Vidali - Plant molecular biology, 2021 - Springer
Key message Here we review, from a quantitative point of view, the cell biology of
protonemal tip growth in the model moss Physcomitrium patens. We focus on the role of the …

In pursuit of designing multicellular engineered living systems: A fluid mechanical perspective

JC Serrano, SK Gupta, RD Kamm… - Annual Review of Fluid …, 2021 - annualreviews.org
From intracellular protein signaling to embryonic symmetry-breaking, fluid transport
ubiquitously drives biological events in living systems. We provide an overview of the …

[HTML][HTML] Trajectory Analysis in Single-Particle Tracking: From Mean Squared Displacement to Machine Learning Approaches

C Schirripa Spagnolo, S Luin - International Journal of Molecular …, 2024 - mdpi.com
Single-particle tracking is a powerful technique to investigate the motion of molecules or
particles. Here, we review the methods for analyzing the reconstructed trajectories, a …

Endosome-ER interactions define a cellular energy landscape to guide cargo transport

Y Shen, Y Wen, Q Zhao, P Huang, PY Lai, P Tong - bioRxiv, 2023 - biorxiv.org
Molecular motor-driven cargo must navigate a complex intracellular environment, which is
often crowded, heterogeneous and fluctuating, to fulfill their diverse functions in a cell. To …

Numerical method for vesicle movement analysis in a complex cytoskeleton network

S Lee, H Kim, H Higuchi - Optics express, 2018 - opg.optica.org
The detection of the precise movement of a vesicle during transport in a live cell provides
key information for the intracellular delivery process. Here we report a novel numerical …

In vivo interactions between myosin XI, vesicles and filamentous actin are fast and transient in Physcomitrella patens

JP Bibeau, F Furt, SI Mousavi… - Journal of Cell …, 2020 - journals.biologists.com
The actin cytoskeleton and active membrane trafficking machinery are essential for
polarized cell growth. To understand the interactions between myosin XI, vesicles and actin …