Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature

SA Sabe, J Feng, FW Sellke… - American Journal of …, 2022 - journals.physiology.org
Coronary microvascular disease (CMD), which affects the arterioles and capillary
endothelium that regulate myocardial perfusion, is an increasingly recognized source of …

Angiography-derived and sensor-wire methods to assess coronary Microvascular dysfunction in patients with acute myocardial infarction

R Scarsini, L Portolan, F Della Mora, F Marin… - Cardiovascular …, 2023 - jacc.org
ST-segment elevation myocardial infarction (STEMI) treatment with primary percutaneous
coronary intervention has dramatically impacted prognosis. However, despite satisfactory …

Artificial intelligence for contrast-free MRI: scar assessment in myocardial infarction using deep learning–based virtual native enhancement

Q Zhang, MK Burrage, M Shanmuganathan… - Circulation, 2022 - Am Heart Assoc
Background: Myocardial scars are assessed noninvasively using cardiovascular magnetic
resonance late gadolinium enhancement (LGE) as an imaging gold standard. A contrast …

Angiography-derived index of microcirculatory resistance (IMRangio) as a novel pressure-wire-free tool to assess coronary microvascular dysfunction in acute …

R Scarsini, M Shanmuganathan, RA Kotronias… - The international journal …, 2021 - Springer
To investigate the diagnostic accuracy of (1) hyperaemic angiography-derived index of
microcirculatory resistance (IMRangio) in defining coronary microvascular dysfunction …

In vivo validation of a novel computational approach to assess microcirculatory resistance based on a single angiographic view

Y Fan, S Fezzi, P Sun, N Ding, X Li, X Hu… - Journal of Personalized …, 2022 - mdpi.com
(1) Background: In spite of the undeniable clinical value of the index of microvascular
resistance (IMR) in assessing the status of coronary microcirculation, its use globally …

Long-term clinical outcomes in patients with an acute ST-segment-elevation myocardial infarction stratified by angiography-derived index of microcirculatory …

RA Kotronias, D Terentes-Printzios… - Frontiers in …, 2021 - frontiersin.org
Aims: Despite the prognostic value of coronary microvascular dysfunction (CMD) in patients
with ST-segment-elevation myocardial infarction (STEMI), its assessment with pressure-wire …

The index of microcirculatory resistance after primary PCI: a pooled analysis of individual patient data

M El Farissi, FM Zimmermann, GL De Maria… - Cardiovascular …, 2023 - jacc.org
Background Despite treatment with primary percutaneous coronary intervention (PCI) in
patients with ST-segment elevation myocardial infarction (STEMI), the risk of heart failure …

Angiography-derived index of microcirculatory resistance to define the risk of early discharge in STEMI

R Scarsini, RA Kotronias, F Della Mora… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Patients with ST-segment–elevation myocardial infarction but no coronary
microvascular injury are at low risk of early cardiovascular complications (ECC). We aim to …

Coronary microvascular dysfunction and hypertension: a bond more important than we think

M Zdravkovic, V Popadic, S Klasnja, A Klasnja… - Medicina, 2023 - mdpi.com
Coronary microvascular dysfunction (CMD) is a clinical entity linked with various risk factors
that significantly affect cardiac morbidity and mortality. Hypertension, one of the most …

Coronary microcirculation: the next frontier in the management of STEMI

D Milasinovic, O Nedeljkovic, R Maksimovic… - Journal of Clinical …, 2023 - mdpi.com
Although the widespread adoption of timely invasive reperfusion strategies over the last two
decades has significantly improved the prognosis of patients with ST-segment elevation …