Viral infections can cause serious diseases for humans and animals. Accurate and early
detection of viruses is often crucial for clinical diagnosis and therapy. Aptamers are mostly …

Paper based lateral flow assays (LFAs) have achieved grand success in point-of-care
diagnostics; nevertheless, they are still facing challenges. This review outlines current major …

A specific aptameric sequence has been immobilized on short polyethyleneglycol (PEG)
interface on gold nano-film deposited on a D-shaped plastic optical fiber (POFs) probe, and …

Nucleic acids play a central role in all domains of life, either as genetic blueprints or as
regulators of various biochemical pathways. The 826chemical makeup of ribonucleic acid …

Nucleic acid aptamers are single-stranded DNA or RNA molecules identified to recognize
with high affinity specific targets including proteins, small molecules, ions, whole cells and …

Aptamers are target specific ssDNA, RNA or peptide sequences generated by an in vitro
selection and amplification method called SELEX (Systematic Evolution of Ligands by …

Today, the treatment of bacterial infections is a major challenge, due to growing rate of
multidrug-resistant bacteria, complication of treatment and increased healthcare costs …

Targeted therapy is highly desirable, as it allows for selective cytotoxicity on diseased cells
without off-target side effects. Nucleolin is a remarkable target for cancer therapy given its …

Viruses are pathogenic microorganisms that can inhabit and replicate in human bodies
causing a number of widespread infectious diseases such as influenza, gastroenteritis …

Affinity reagents are essential tools in both basic and applied research; however, there is a
growing concern about the reproducibility of animal-derived monoclonal antibodies. The …