Parkinson's disease

BR Bloem, MS Okun, C Klein - The Lancet, 2021 - thelancet.com
Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical
presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; …

A meta-analysis identifies factors predicting the future development of freezing of gait in Parkinson's disease

T Herman, Y Barer, M Bitan, S Sobol, N Giladi… - npj Parkinson's …, 2023 - nature.com
Freezing of gait (FOG) is a debilitating problem that is common among many, but not all,
people with Parkinson's disease (PD). Numerous attempts have been made at treating FOG …

Digital technology in movement disorders: updates, applications, and challenges

JL Adams, KJ Lizarraga, EM Waddell, TL Myers… - Current neurology and …, 2021 - Springer
Abstract Purpose of Review Digital technology affords the opportunity to provide objective,
frequent, and sensitive assessment of disease outside of the clinic environment. This article …

Multidisciplinary care for people with Parkinson's disease: the new kids on the block!

DLM Radder, NM de Vries, NP Riksen… - Expert review of …, 2019 - Taylor & Francis
Introduction: Parkinson's disease (PD) is a chronic multisystem disorder that causes a wide
variety of motor and non-motor symptoms. Over time, the progressive nature of the disease …

Deep phenotyping of Parkinson's disease

ER Dorsey, L Omberg, E Waddell… - Journal of …, 2020 - journals.sagepub.com
Phenotype is the set of observable traits of an organism or condition. While advances in
genetics, imaging, and molecular biology have improved our understanding of the …

Redefining the hypotheses driving Parkinson's diseases research

SL Farrow, AA Cooper, JM O'Sullivan - NPJ Parkinson's disease, 2022 - nature.com
Parkinson's disease (PD) research has largely focused on the disease as a single entity
centred on the development of neuronal pathology within the central nervous system …

A multidimensional gender analysis of health technology self-efficacy among people with Parkinson's disease

I Göttgens, SKL Darweesh, BR Bloem… - Journal of …, 2024 - Springer
Background Digital health technologies (DHT) enable self-tracking of bio-behavioral states
and pharmacotherapy outcomes in various diseases. However, the role of gender …

Precision medicine in the care of rheumatoid arthritis: focus on prediction and prevention of future clinically-apparent disease

M Mahler, L Martinez-Prat, JA Sparks, KD Deane - Autoimmunity Reviews, 2020 - Elsevier
There is an emerging understanding that an individual's risk for future rheumatoid arthritis
(RA) can be determined using a combination of factors while they are still in a state where …

Targeting immunoproteasome in neurodegeneration: A glance to the future

GR Tundo, P Cascio, D Milardi, AM Santoro… - Pharmacology & …, 2023 - Elsevier
The immunoproteasome is a specialized form of proteasome equipped with modified
catalytic subunits that was initially discovered to play a pivotal role in MHC class I antigen …

A long way to go: patient perspectives on digital health for Parkinson's disease

S Riggare, J Stamford… - Journal of Parkinson's …, 2021 - content.iospress.com
Digital health promises to improve healthcare, health, and wellness through the use of
digital technologies. The purpose of this commentary is to review and discuss the field of …