Swynghedauw, Bernard. Molecular Mechanisms of Myocardial Remodeling. Physiol. Rev.
79: 215–262, 1999.—“Remodeling” implies changes that result in rearrangement of …

Adrenergic receptors (AR) are G-protein-coupled receptors (GPCRs) that have a crucial role
in cardiac physiology in health and disease. Alpha 1-ARs signal through Gα q, and signaling …

Neuregulins (ie neuregulin-1 (NRG1), also called neu differentiation factor, heregulin, glial
growth factor, and acetylcholine receptor-inducing activity) are known to induce growth and …

Background—α1-adrenergic receptors (α1ARs) regulate blood pressure, regional vascular
resistance, and venous capacitance; the exact subtype (α1a, α1b, α1 d) mediating these …

α1-Adrenoceptors are one of three subfamilies of receptors (α1, α2, β) mediating responses
to adrenaline and noradrenaline. Three α1-adrenoceptor subtypes are known (α1A, α1B …

Purpose: We compared the expression level of α1-adrenoceptor (AR) subtype mRNA to that
of β-AR subtype mRNA in control and obstructed human bladders, and examined whether …

Background—We recently reported that cardiomyocytes could be differentiated from bone
marrow mesenchymal stem cells in vitro by 5-azacytidine treatment. In native …

The direct effects of catecholamines on cardiac myocytes may contribute to both normal
physiologic adaptation and pathologic remodeling, and may be associated with cellular …

Catecholamines and α 1-adrenergic receptors (α 1-ARs) cause cardiac hypertrophy in
cultured myocytes and transgenic mice, but heart size is normal in single KOs of the main α …

Adrenergic receptors (ARs) are members of the G-protein-coupled receptor family, which
includes α1ARs, α2ARs, β1ARs, β2ARs, β3ARs, adenosine, muscarinic, angiotensin …