Tumor microenvironment: bone marrow-mesenchymal stem cells as key players

P Barcellos-de-Souza, V Gori, F Bambi… - Biochimica et Biophysica …, 2013 - Elsevier
Tumor progression is a multistep phenomenon in which tumor-associated stromal cells
perform an intricate cross-talk with tumor cells, supplying appropriate signals that may …

Closing the door with CRISPR: genome editing of CCR5 and CXCR4 as a potential curative solution for HIV

JJ Freen-van Heeren - BioTech, 2022 - mdpi.com
Human immunodeficiency virus (HIV) infection can be controlled by anti-retroviral therapy.
Suppressing viral replication relies on life-long medication, but anti-retroviral therapy is not …

Macrophage subpopulations are essential for infarct repair with and without stem cell therapy

T Ben-Mordechai, R Holbova, N Landa-Rouben… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to investigate the hypothesis that the favorable effects of
mesenchymal stromal cells (MSCs) on infarct repair are mediated by macrophages …

Resident macrophages in the cochlear blood-labyrinth barrier and their renewal via migration of bone-marrow-derived cells

X Shi - Cell and tissue research, 2010 - Springer
A large population of perivascular cells was found to be present in the area of the blood-
labyrinth barrier in the stria vascularis of normal adult cochlea. The cells were identified as …

HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation

L Yuan, J Jiang, X Liu, Y Zhang, L Zhang, J Xin, K Wu… - Gut, 2019 - gut.bmj.com
Objective Developing a small animal model that accurately delineates the natural history of
hepatitis B virus (HBV) infection and immunopathophysiology is necessary to clarify the …

[PDF][PDF] Phenotype and differentiation potential of stromal populations obtained from various zones of human umbilical cord: an overview

MT Conconi, R Di Liddo, M Tommasini… - The Open Tissue …, 2011 - researchgate.net
Fibroblast-like cells with properties similar to mesenchymal stromal cells (MSCs) are present
in human umbilical cord (hUC). In accordance with the international minimal criteria for …

Functional characteristics of mesenchymal stem cells derived from bone marrow of patients with myelodysplastic syndromes

ZG Zhao, W Xu, HP Yu, BL Fang, SH Wu, F Li, WM Li… - Cancer letters, 2012 - Elsevier
Mesenchymal stem cells (MSCs) have emerged as excellent candidates for clinical
application because of their capabilities of immunomodulatory and supporting …

The impact of statins on biological characteristics of stem cells provides a novel explanation for their pleiotropic beneficial and adverse clinical effects

R Izadpanah, DJ Schächtele… - … of Physiology-Cell …, 2015 - journals.physiology.org
Statins reduce atherosclerotic events and cardiovascular mortality. Their side effects include
memory loss, myopathy, cataract formation, and increased risk of diabetes. As …

Telomere length analysis of human mesenchymal stem cells by quantitative PCR

RM Samsonraj, M Raghunath, JH Hui, L Ling… - Gene, 2013 - Elsevier
Human mesenchymal stem cells (hMSCs) have attracted much attention for tissue repair
and wound healing because of their self-renewal capacity and multipotentiality. In order to …

Human umbilical cord stromal stem cell express CD10 and exert contractile properties

VA Farias, JL Linares-Fernandez, JL Penalver… - Placenta, 2011 - Elsevier
BACKGROUND: It has been demonstrated that human umbilical cord stromal stem cells
(UCSSCs) are bio-equivalent to bone marrow mesenchymal stem cells. However, little is …