Brain mechanisms underlying neuropsychiatric symptoms in Alzheimer's disease: a systematic review of symptom-general and–specific lesion patterns

Y Chen, M Dang, Z Zhang - Molecular Neurodegeneration, 2021 - Springer
Neuropsychiatric symptoms (NPSs) are common in patients with Alzheimer's disease (AD)
and are associated with accelerated cognitive impairment and earlier deaths. This review …

The clinical use of structural MRI in Alzheimer disease

GB Frisoni, NC Fox, CR Jack Jr, P Scheltens… - Nature reviews …, 2010 - nature.com
Structural imaging based on magnetic resonance is an integral part of the clinical
assessment of patients with suspected Alzheimer dementia. Prospective data on the natural …

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

G Davies, M Lam, SE Harris, JW Trampush… - Nature …, 2018 - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Suspected non-Alzheimer disease pathophysiology—concept and controversy

CR Jack Jr, DS Knopman, G Chételat… - Nature Reviews …, 2016 - nature.com
Suspected non-Alzheimer disease pathophysiology (SNAP) is a biomarker-based concept
that applies to individuals with normal levels of amyloid-β biomarkers in the brain, but in …

[HTML][HTML] Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI

KM Broadhouse, MF Singh, C Suo, N Gates, W Wen… - NeuroImage: Clinical, 2020 - Elsevier
Dementia affects 47 million individuals worldwide, and assuming the status quo is projected
to rise to 150 million by 2050. Prevention of age-related cognitive impairment in older …

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

A comprehensive analysis of resting state fMRI measures to classify individual patients with Alzheimer's disease

F de Vos, M Koini, TM Schouten, S Seiler… - Neuroimage, 2018 - Elsevier
Alzheimer's disease (AD) patients show altered patterns of functional connectivity (FC) on
resting state functional magnetic resonance imaging (RSfMRI) scans. It is yet unclear which …

Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative

CR Jack Jr, MA Bernstein, BJ Borowski, JL Gunter… - Alzheimer's & …, 2010 - Elsevier
Functions of the Alzheimer's Disease Neuroimaging Initiative (ADNI) magnetic resonance
imaging (MRI) core fall into three categories:(1) those of the central MRI core laboratory at …

The Alzheimer's disease neuroimaging initiative: progress report and future plans

MW Weiner, PS Aisen, CR Jack Jr, WJ Jagust… - Alzheimer's & …, 2010 - Elsevier
The Alzheimer's Disease Neuroimaging Initiative (ADNI) beginning in October 2004, is a 6-
year research project that studies changes of cognition, function, brain structure and …

[HTML][HTML] Magnetic resonance imaging in Alzheimer's disease neuroimaging initiative 2

CR Jack Jr, J Barnes, MA Bernstein, BJ Borowski… - Alzheimer's & …, 2015 - Elsevier
Abstract Introduction Alzheimer's Disease Neuroimaging Initiative (ADNI) is now in its 10th
year. The primary objective of the magnetic resonance imaging (MRI) core of ADNI has been …