DeepDigest: prediction of protein proteolytic digestion with deep learning

J Yang, Z Gao, X Ren, J Sheng, P Xu… - Analytical …, 2021 - ACS Publications
Proteolytic digestion of proteins by one or more proteases is a key step in shotgun
proteomics, in which the proteolytic products, ie, peptides, are taken as the surrogates of …

ProteaseGuru: a tool for protease selection in bottom-up proteomics

RM Miller, K Ibrahim, LM Smith - Journal of proteome research, 2021 - ACS Publications
Bottom-up proteomics is currently the dominant strategy for proteome analysis. It relies
critically upon the use of a protease to digest proteins into peptides, which are then identified …

Harvesting bioactive peptides from sustainable protein sources: Unveiling technological and functional properties through in silico analyses

Hİ Öztürk, A Oraç - Food and Humanity, 2024 - Elsevier
Bioactive peptides, usually characterized by short amino acid sequences, are functional
components obtained from precursor proteins by enzymatic, chemical, or other processing …

Leveraging Pretrained Deep Protein Language Model to Predict Peptide Collision Cross Section

A Nakai-Kasai, K Ogata, Y Ishihama, T Tanaka - bioRxiv, 2024 - biorxiv.org
Collision cross section (CCS) of peptide ions provides an important separation dimension in
liquid chromatography/tandem mass spectrometry-based proteomics that incorporates ion …