[HTML][HTML] Primary sclerosing cholangitis–a comprehensive review

TH Karlsen, T Folseraas, D Thorburn, M Vesterhus - Journal of hepatology, 2017 - Elsevier
Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …

Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management

JE Eaton, JA Talwalkar, KN Lazaridis, GJ Gores… - Gastroenterology, 2013 - Elsevier
Primary sclerosing cholangitis (PSC), first described in the mid-1850s, is a complex liver
disease that is heterogeneous in its presentation. PSC is characterized by chronic …

British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

MH Chapman, D Thorburn, GM Hirschfield… - Gut, 2019 - gut.bmj.com
These guidelines on the management of primary sclerosing cholangitis (PSC) were
commissioned by the British Society of Gastroenterology liver section. The guideline writing …

[HTML][HTML] Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

L Bajer, M Kverka, M Kostovcik, P Macinga… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To characterize the gut bacterial microbiota of patients with primary sclerosing
cholangitis (PSC) and ulcerative colitis (UC). METHODS Stool samples were collected and …

ACG clinical guideline: primary sclerosing cholangitis

KD Lindor, KV Kowdley… - Official journal of the …, 2015 - journals.lww.com
Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and
may require liver transplantation. The cause is unknown, although it is commonly associated …

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

SG Ji, BD Juran, S Mucha, T Folseraas, L Jostins… - Nature …, 2017 - nature.com
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct
destruction;∼ 75% of patients have comorbid inflammatory bowel disease (IBD). We …

EASL Clinical Practice Guidelines: management of cholestatic liver diseases

European Association For The Study Of The Liver - Journal of hepatology, 2009 - Elsevier
EASL Clinical Practice Guidelines (CPG) on the management of cholestatic liver diseases
define the use of diagnostic, therapeutic and preventive modalities, including non-invasive …

[PDF][PDF] Diagnosis and management of primary sclerosing cholangitis

R Chapman, J Fevery, A Kalloo, DM Nagorney… - …, 2010 - Wiley Online Library
This guideline has been approved by the American Association for the Study of Liver
Diseases and represents the position of the Association. These recommendations provide a …

The epidemiology of cholangiocarcinoma

Y Shaib, HB El-Serag - Seminars in liver disease, 2004 - thieme-connect.com
The incidence rates of cholangiocarcinoma (CC) vary greatly among different areas of the
world, and this variation is related to distribution of risk factors. Intrahepatic …

Bile acids and intestinal microbiota in autoimmune cholestatic liver diseases

Y Li, R Tang, PSC Leung, ME Gershwin, X Ma - Autoimmunity reviews, 2017 - Elsevier
Autoimmune cholestatic liver diseases, including primary biliary cholangitis (PBC) and
primary sclerosing cholangitis (PSC), are manifested as an impairment of normal bile flow …