Improvements in outcomes for patients who have cystic fibrosis (CF) have been striking in
the last 30 years. Median survival now approaches the fifth decade of life. Advances in the …

Cystic fibrosis is now the most common cause of chronic obstructive pulmonary disease
(COPD) and of pancreatic insufficiency in the first three decades of life in the United States …

This text, the second of 2 volumes comprising contributions from 224 individuals in 10
countries, discusses infectious diseases of childhood according to specific microorganisms …

Cystic fibrosis: A 2002 update - The Journal of Pediatrics Skip to Main Content Skip to Main
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Neonatal screening for cystic fibrosis (CF) has become feasible through analyzing dried
blood specimens for immunoreactive trypsinogen (IRT), but the benefits and risks of such a …

Screening of the newborn for cystic fibrosis by measurement of immunoreactive trypsin has
been undertaken on alternate weeks in Wales and the West Midlands for five years since …

Our previous studies suggested that assay of immunoreactive trypsin (IRT) in dried blood
spots might be a valuable neonatal screening test for cystic fibrosis (CF). We have …

Detection of elevated levels of immunoreactive trypsinogen (IRT) in dried neonatal blood
spots has been used as a screening test for cystic fibrosis. In other cystic fibrosis newborn …

Objectives. To evaluate neonatal screening for cystic fibrosis (CF), including study of the
screening procedures and characteristics of false-positive infants, over the past 10 years in …

Seventy-five thousand 5-day-old babies were screened for cystic fibrosis by blood spot
immunoreactive trypsin (IRT) assay as part of a statewide screening program. IRT was …