Eosinophils are a prominent cell type in particular host responses such as the response to
helminth infection and allergic disease. Their effector functions have been attributed to their …

One of the functions of the immune system is to recognize and destroy abnormal or infected
cells to maintain homeostasis. This is accomplished by cytotoxic lymphocytes. Cytotoxicity is …

Leukocyte immunoglobulin-like receptor B (LILRB), a family of immune checkpoint
receptors, contributes to acute myeloid leukemia (AML) development, but the specific …

Eosinophils are innate immune leukocytes implicated in the initiation and maintenance of
type 2 immune responses, including asthma and allergy. The ability to store and rapidly …

Leukocyte immunoglobulin (Ig)‐like receptors [LILRs, also known as Ig‐like transcripts
(ILTs)] are a family of inhibitory and stimulatory receptors encoded within the leukocyte …

Eicosanoids (prostaglandins, leukotrienes and lipoxins) are signaling lipids derived from
arachidonic acid metabolism that have important roles in physiological and pathological …

The leukocyte immunoglobulin-like receptor (LILR) family comprises a set of paired
immunomodulatory receptors expressed among human myeloid and lymphocyte cell …

Immunoglobulin-like transcripts are a family of inhibitory and stimulatory cell surface immune
receptors. Transcripts for one member of this family, ILT7, are selectively expressed in …

Eosinophils, innate immune leukocytes elicited by Th2 cells, have long been associated with
the effector arm of Th2 immune responses. However, accumulating data over the past …

The initial steps in the biosynthesis of leukotrienes from arachidonic acid are carried out by
the enzyme 5-lipoxygenase (5-LO). In intact cells, the helper protein 5-LO activating protein …