Age-related macular degeneration is one of the leading causes of vision loss in the elderly.
Genetics, environmental insults, and age-related issues are risk factors for the development …

Retinal ganglion cells (RGCs) are a population of neurons of the central nervous system
(CNS) extending with their soma to the inner retina and with their axons to the optic nerve …

Excessive light exposure can damage photoreceptors and lead to blindness. Oxidative
stress serves a key role in photo-induced retinal damage. Free radical scavengers have …

Oxidative stress and neuroinflammation contribute significantly to the development and
progression of diabetic retinopathy. Fenofibrate has received great attention as it benefits …

Age-related diseases, such as Parkinson's disease, Alzheimer's disease, cardiovascular
diseases, cancers, and age-related macular disease, have become increasingly prominent …

ABSTRACT Müller glia constitute the main glial cells of the retina. They are spatially
distributed along this tissue, facilitating their close membrane interactions with all retinal …

Rationale: Müller cells play an essential role in maintaining the health of retinal
photoreceptors. Dysfunction of stressed Müller cells often results in photoreceptor …

Dry age‐related macular degeneration (dAMD) is a chronic degenerative ophthalmopathy
that leads to serious burden of visual impairment. Antioxidation in retinal pigment epithelium …

Objective: To discover the possible underlying mechanism of Chlorogenic acid (CGA) in
protecting against oxidative stress injury in glaucoma. Methods: LncRNA TUG1 and Nrf2 …

The nuclear erythroid 2-related-factor (Nrf2) transcription factor/hemoxygenase 1 (HO-1) is a
key regulator of an important neuroprotection response by driving the interpretation of …