[HTML][HTML] Biological and mechanical performance and degradation characteristics of calcium phosphate cements in large animals and humans

L Schröter, F Kaiser, S Stein, U Gbureck, A Ignatius - Acta Biomaterialia, 2020 - Elsevier
Calcium phosphate cements (CPCs) have been used to treat bone defects and support
bone regeneration because of their good biocompatibility and osteointegrative behavior …

Preclinical and translational studies in small ruminants (sheep and goat) as models for osteoporosis research

IR Dias, JA Camassa, JA Bordelo, PS Babo… - Current Osteoporosis …, 2018 - Springer
Abstract Purpose of the Review This review summarizes research on the use of sheep and
goats as large animal models of human osteoporosis for preclinical and translational …

Electrospun nanofibrous P (DLLA–CL) balloons as calcium phosphate cement filled containers for bone repair: in vitro and in vivo studies

X Liu, D Wei, J Zhong, M Ma, J Zhou… - … applied materials & …, 2015 - ACS Publications
The spinal surgeon community has expressed significant interest in applying calcium
phosphate cement (CPC) for the treatment of vertebral compression fractures (VCFs) and …

[HTML][HTML] A comprehensive systematic review of marketed bone grafts for load-bearing critical-sized bone defects

D Ninarello, A Ballardini, G Morozzi… - journal of the mechanical …, 2024 - Elsevier
Abstract Treatment of critical-sized bone defects typically involves implantation of a bone
graft. Various types of bone grafts are nowadays marketed, categorized by their origin as …

Injectable bioactive polymethyl methacrylate–hydrogel hybrid bone cement loaded with BMP-2 to improve osteogenesis for percutaneous vertebroplasty and …

X Sun, X Zhang, X Jiao, J Ma, X Liu, H Yang… - Bio-Design and …, 2022 - Springer
Polymethyl methacrylate (PMMA) bone cement is used in augmenting and stabilizing
fractured vertebral bodies through percutaneous vertebroplasty (PVP) and percutaneous …

Pre-clinical evaluation of biological bone substitute materials for application in highly loaded skeletal sites

S de Lacerda Schickert, JJJP van den Beucken… - Biomolecules, 2020 - mdpi.com
The development of bone substitute materials (BSMs) intended for load-bearing bone
defects is highly complicated, as biological and mechanical requirements are often …

Ready‐To‐Use and Rapidly Biodegradable Magnesium Phosphate Bone Cement: In Vivo Evaluation in Sheep

L Schröter, F Kaiser, AL Preißler… - Advanced …, 2023 - Wiley Online Library
In clinical practice, hydroxyapatite (HA) cements for bone defect treatment are frequently
prepared by mixing a powder component and a liquid component shortly before …

Intraoperative PEEP-ventilation during PMMA-injection for augmented pedicle screws: improvement of leakage rate in spinal surgery

A El Saman, A Kelm, S Meier, AL Sander… - European Journal of …, 2013 - Springer
Background Within the last two decades the use of polymethylmethacrylate (PMMA) in the
treatment of osteoporotic vertebral fractures has been established widely. Several …

Decreased extrusion of calcium phosphate cement versus high viscosity PMMA cement into spongious bone marrow—an ex vivo and in vivo study in sheep vertebrae

L Xin, M Bungartz, S Maenz, V Horbert, M Hennig… - The Spine Journal, 2016 - Elsevier
Abstract Background Context Vertebroplasty or kyphoplasty of osteoporotic vertebral
fractures bears the risk of pulmonary cement embolism (3.5%–23%) caused by leakage of …

[HTML][HTML] Effect of polymethylmethacrylate-hydroxyapatite composites on callus formation and compressive strength in goat vertebral body

IS Komang-Agung, L Hydravianto… - Malaysian …, 2018 - ncbi.nlm.nih.gov
Introduction: Percutaneous vertebroplasty (PV) is one of the available treatments for
vertebral compression fracture (VCF). Polymethylmethacrylate (PMMA) is the most common …