Biomarkers in sarcoidosis

A Chopra, A Kalkanis, MA Judson - Expert review of clinical …, 2016 - Taylor & Francis
Introduction: Numerous biomarkers have been evaluated for the diagnosis, assessment of
disease activity, prognosis, and response to treatment in sarcoidosis. In this report, we …

Do renin–angiotensin system inhibitors influence the recurrence, metastasis, and survival in cancer patients?: Evidence from a meta-analysis including 55 studies

H Sun, T Li, R Zhuang, W Cai, Y Zheng - Medicine, 2017 - journals.lww.com
Background: Renin–angiotensin system inhibitors (RAS inhibitors) are antihypertensive
agents with potential antitumor effects. However, various studies have yielded conflicting …

Gastrointestinal cancers, ACE-2/TMPRSS2 expression and susceptibility to COVID-19

S Shafiee, L Cegolon, M Khafaei, N Gholami… - Cancer cell …, 2021 - Springer
Recent studies on the pathophysiology of COVID-19 are indicating that the Angiotensin
convertase enzyme 2 (ACE-2) and transmembrane serine protease 2 (TMPRSS2) can act as …

Mdact: A new principle of adjunctive cancer treatment using combinations of multiple repurposed drugs, with an example regimen

RE Kast, A Alfieri, HI Assi, TC Burns, AM Elyamany… - Cancers, 2022 - mdpi.com
Simple Summary We present eight core attributes of cancer growth that we must address for
a more effective treatment than we currently have. To do this we outline why a regimen …

Survival analysis of 1140 patients with biliary Cancer and Benefit from Concurrent Renin-Angiotensin Antagonists, Statins, or aspirin with systemic therapy

V Gunchick, RL McDevitt, E Choi, K Winslow… - The …, 2023 - academic.oup.com
Background Patients with advanced biliary tract cancers (BTCs) have poor prognoses and
limited therapeutic options. Renin-angiotensin antagonists (ACE-I/ARBs), statins, and …

ErBb family proteins in cholangiocarcinoma and clinical implications

W Jin - Journal of Clinical Medicine, 2020 - mdpi.com
The erythroblastic leukemia viral oncogene homolog (ErBb) family consists of the receptor
tyrosine kinases (RTK) epidermal growth factor receptor (EGFR; also called ERBB1) …

[HTML][HTML] Comprehensive landscape of the renin-angiotensin system in Pan-cancer: a potential downstream mediated mechanism of SARS-CoV-2

Y Cui, F Chen, J Gao, M Lei, D Wang, X Jin… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Background: SARS-CoV-2, the cause of the worldwide COVID-19 pandemic, utilizes the
mechanism of binding to ACE2 (a crucial component of the renin-angiotensin system [RAS]) …

The roles of beta-adrenergic receptors in tumorigenesis and the possible use of beta-adrenergic blockers for cancer treatment: possible genetic and cell-signaling …

K quốc Lu'o'ng, LTH Nguyễn - Cancer management and research, 2012 - Taylor & Francis
Cancer is the leading cause of death in the USA, and the incidence of cancer increases
dramatically with age. Beta-adrenergic blockers appear to have a beneficial clinical effect in …

Assessment of serum angiotensin-converting enzyme in patients with epithelial ovarian cancer

F Beyazit, S Ayhan, HT Celik, T Gungor - Archives of Gynecology and …, 2015 - Springer
Background and aims Clinicopathologic and molecular studies have provided new insights
and understanding on the pathological events during ovarian carcinogenesis. Moreover …

[HTML][HTML] Diagnostic and prognostic serum marker of cholangiocarcinoma

X Zeng, H Tao - Oncology letters, 2015 - spandidos-publications.com
Cholangiocarcinoma (CCA) is a fatal disease that is typically diagnosed late and treated
ineffectively. As the morbidity and mortality rates for CCA rise markedly, patietns with CCA …