Retinal capillary perfusion: spatial and temporal heterogeneity

DY Yu, SJ Cringle, KY Paula… - Progress in retinal and …, 2019 - Elsevier
The central role of the cardiovascular system is to maintain adequate capillary perfusion.
The spatially and temporally heterogeneous nature of capillary perfusion has been reported …

Can OCT angiography be made a quantitative blood measurement tool?

J Zhu, CW Merkle, MT Bernucci, SP Chong… - Applied sciences, 2017 - mdpi.com
Featured Application Optical Coherence Tomography Angiography (OCTA) is a technique
for label-free vascular imaging in fields such as ophthalmology, gastroenterology, cancer …

Aging-associated changes in cerebral vasculature and blood flow as determined by quantitative optical coherence tomography angiography

Y Li, WJ Choi, W Wei, S Song, Q Zhang, J Liu… - Neurobiology of …, 2018 - Elsevier
Normal aging is associated with significant alterations in brain's vascular structure and
function, which can lead to compromised cerebral circulation and increased risk of …

Quantitative blood flow estimation in vivo by optical speckle image velocimetry

MM Qureshi, Y Liu, KD Mac, M Kim, AM Safi, E Chung - Optica, 2021 - opg.optica.org
Speckle-based methods are popular non-invasive, label-free full-field optical techniques for
imaging blood flow maps at single vessel resolution with a high temporal resolution …

Interplay of temperature, thermal‐stresses and strains in laser‐assisted modification of collagenous tissues: Speckle‐contrast and OCT‐based studies

OI Baum, VY Zaitsev, AV Yuzhakov… - Journal of …, 2020 - Wiley Online Library
Moderate heating of collagenous tissues such as cartilage and cornea by infrared laser
irradiation can produce biologically nondestructive structural rearrangements and relaxation …

Optical coherence tomography angiography-based capillary velocimetry

RK Wang, Q Zhang, Y Li… - Journal of biomedical …, 2017 - spiedigitallibrary.org
Challenge persists in the field of optical coherence tomography (OCT) when it is required to
quantify capillary blood flow within tissue beds in vivo. We propose a useful approach to …

Cortical microvascular blood flow velocity mapping by combining dynamic light scattering optical coherence tomography and two-photon microscopy

Q Pian, M Alfadhel, J Tang, GV Lee, B Li… - Journal of …, 2023 - spiedigitallibrary.org
Significance The accurate large-scale mapping of cerebral microvascular blood flow velocity
is crucial for a better understanding of cerebral blood flow (CBF) regulation. Although optical …

Understanding the neurovascular unit at multiple scales: advantages and limitations of multi-photon and functional ultrasound imaging

A Urban, L Golgher, C Brunner, A Gdalyahu… - Advanced drug delivery …, 2017 - Elsevier
Developing efficient brain imaging technologies by combining a high spatiotemporal
resolution and a large penetration depth is a key step for better understanding the …

Capillary flow homogenization during functional activation revealed by optical coherence tomography angiography based capillary velocimetry

Y Li, W Wei, RK Wang - Scientific reports, 2018 - nature.com
Elaborate modeling study suggests an important role of capillary transit time heterogeneity
(CTTH) reduction in brain oxygenation during functional hyperemia. Here, we use optical …

Capillary red blood cell velocimetry by phase-resolved optical coherence tomography

J Tang, SE Erdener, B Fu, DA Boas - Optics letters, 2017 - opg.optica.org
We present a phase-resolved optical coherence tomography (OCT) method to extend
Doppler OCT for the accurate measurement of the red blood cell (RBC) velocity in cerebral …