The origin of animal multicellularity and cell differentiation

T Brunet, N King - Developmental cell, 2017 - cell.com
Over 600 million years ago, animals evolved from a unicellular or colonial organism whose
cell (s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar …

Tissue biology: in search of a new paradigm

M Adler, AR Chavan, R Medzhitov - Annual Review of Cell and …, 2023 - annualreviews.org
Animal tissues are made up of multiple cell types that are increasingly well-characterized,
yet our understanding of the core principles that govern tissue organization is still …

[HTML][HTML] Divergent genomic trajectories predate the origin of animals and fungi

E Ocaña-Pallarès, TA Williams, D López-Escardó… - Nature, 2022 - nature.com
Animals and fungi have radically distinct morphologies, yet both evolved within the same
eukaryotic supergroup: Opisthokonta,. Here we reconstructed the trajectory of genetic …

The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition

N Ros-Rocher, A Pérez-Posada, MM Leger… - Open …, 2021 - royalsocietypublishing.org
How animals evolved from a single-celled ancestor, transitioning from a unicellular lifestyle
to a coordinated multicellular entity, remains a fascinating question. Key events in this …

The origin of metazoan multicellularity: a potential microbial black swan event

I Ruiz-Trillo, K Kin, E Casacuberta - Annual Review of …, 2023 - annualreviews.org
The emergence of animals from their unicellular ancestors is a major evolutionary event.
Thanks to the study of diverse close unicellular relatives of animals, we now have a better …

Gene family innovation, conservation and loss on the animal stem lineage

DJ Richter, P Fozouni, MB Eisen, N King - elife, 2018 - elifesciences.org
Choanoflagellates, the closest living relatives of animals, can provide unique insights into
the changes in gene content that preceded the origin of animals. However, only two …

Genetic tool development in marine protists: emerging model organisms for experimental cell biology

D Faktorová, RER Nisbet, JA Fernández Robledo… - Nature …, 2020 - nature.com
Diverse microbial ecosystems underpin life in the sea. Among these microbes are many
unicellular eukaryotes that span the diversity of the eukaryotic tree of life. However, genetic …

The triple helix of collagens–an ancient protein structure that enabled animal multicellularity and tissue evolution

AL Fidler, SP Boudko, A Rokas… - Journal of cell …, 2018 - journals.biologists.com
The cellular microenvironment, characterized by an extracellular matrix (ECM), played an
essential role in the transition from unicellularity to multicellularity in animals (metazoans) …

Stepwise emergence of the neuronal gene expression program in early animal evolution

SR Najle, X Grau-Bové, A Elek, C Navarrete… - Cell, 2023 - cell.com
The assembly of the neuronal and other major cell type programs occurred early in animal
evolution. We can reconstruct this process by studying non-bilaterians like placozoans …

Reconstruction of the ancestral metazoan genome reveals an increase in genomic novelty

J Paps, PWH Holland - Nature communications, 2018 - nature.com
Understanding the emergence of the Animal Kingdom is one of the major challenges of
modern evolutionary biology. Many genomic changes took place along the evolutionary …