[PDF][PDF] Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research

Z Yu, M Guindani, SF Grieco, L Chen, TC Holmes, X Xu - Neuron, 2022 - cell.com
In basic neuroscience research, data are often clustered or collected with repeated
measures, hence correlated. The most widely used methods such as t test and ANOVA do …

[HTML][HTML] The world cancer research fund/American institute for cancer research third expert report on diet, nutrition, physical activity, and cancer: impact and future …

SK Clinton, EL Giovannucci, SD Hursting - The Journal of nutrition, 2020 - Elsevier
ABSTRACT The Third Expert Report on Diet, Nutrition, Physical Activity, and Cancer: A
Global Perspective by the World Cancer Research Fund (WCRF) and the American Institute …

Challenges for assessing replicability in preclinical cancer biology

TM Errington, A Denis, N Perfito, E Iorns, BA Nosek - elife, 2021 - elifesciences.org
We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of
preclinical research in cancer biology. The initial aim of the project was to repeat 193 …

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

N Percie du Sert, V Hurst, A Ahluwalia… - Journal of Cerebral …, 2020 - journals.sagepub.com
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal
Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve …

[HTML][HTML] Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

NP Du Sert, A Ahluwalia, S Alam, MT Avey… - PLoS …, 2020 - journals.plos.org
Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

[HTML][HTML] A manifesto for reproducible science

MR Munafò, BA Nosek, DVM Bishop, KS Button… - Nature human …, 2017 - nature.com
Improving the reliability and efficiency of scientific research will increase the credibility of the
published scientific literature and accelerate discovery. Here we argue for the adoption of …

[HTML][HTML] The current state of animal models in research: A review

NB Robinson, K Krieger, FM Khan, W Huffman… - International Journal of …, 2019 - Elsevier
Animal models have provided invaluable information in the pursuit of medical knowledge
and alleviation of human suffering. The foundations of our basic understanding of disease …

[HTML][HTML] The laboratory rat: Age and body weight matter

A Ghasemi, S Jeddi, K Kashfi - EXCLI journal, 2021 - ncbi.nlm.nih.gov
Animal experimentation helps us to understand human biology. Rodents and, in particular,
rats are among the most common animals used in animal experiments. Reporting data on …

[HTML][HTML] Inclusion of females does not increase variability in rodent research studies

AK Beery - Current opinion in behavioral sciences, 2018 - Elsevier
Highlights•Female subjects are underrepresented in animal research.•Recent studies
demonstrate that unstaged female rodents are no more variable than males.•Factorial …

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

JC McGrath, E Lilley - British journal of pharmacology, 2015 - Wiley Online Library
The ARRIVE guidelines have been implemented in BJP for 4 years with the aim of
increasing transparency in reporting experiments involving animals. BJP has assessed our …