Physical exercise and neuroinflammation in major depressive disorder

ZM Ignácio, RS da Silva, ME Plissari, J Quevedo… - Molecular …, 2019 - Springer
Major depressive disorder (MDD) is a prevalent psychiatric disorder associated with varied
prognosis, chronic course, and duration of illness with reduced quality of life. One factor that …

The effects of exercise on cognition in Parkinson's disease: a systematic review

DK Murray, MA Sacheli, JJ Eng, AJ Stoessl - Translational …, 2014 - Springer
Cognitive impairments are highly prevalent in Parkinson's disease (PD) and can
substantially affect a patient's quality of life. These impairments remain difficult to manage …

[HTML][HTML] Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: involvement of hippocampal plasticity via AKT, CREB and …

AS Aguiar Jr, AA Castro, EL Moreira, V Glaser… - Mechanisms of ageing …, 2011 - Elsevier
In the present study, we investigated whether mild-intensity physical exercise represents a
successful strategy to enhance spatial learning and memory and hippocampal plasticity in …

“Control” laboratory rodents are metabolically morbid: why it matters

B Martin, S Ji, S Maudsley… - Proceedings of the …, 2010 - National Acad Sciences
Failure to recognize that many standard control rats and mice used in biomedical research
are sedentary, obese, glucose intolerant, and on a trajectory to premature death may …

Enhancement of cognitive function in models of brain disease through environmental enrichment and physical activity

TYC Pang, AJ Hannan - Neuropharmacology, 2013 - Elsevier
This review will provide an overview of the non-drug based approaches that have been
demonstrated to enhance cognitive function of the compromised brain, primarily focussed on …

Effects of caffeine in Parkinson's disease: from neuroprotection to the management of motor and non-motor symptoms

RDS Prediger - Journal of Alzheimer's Disease, 2010 - content.iospress.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
approximately 1% of the population older than 60 years. Classically, PD is considered to be …

Exercise as a positive modulator of brain function

KA Alkadhi - Molecular neurobiology, 2018 - Springer
Various forms of exercise have been shown to prevent, restore, or ameliorate a variety of
brain disorders including dementias, Parkinson's disease, chronic stress, thyroid disorders …

Mechanisms of oxidative stress resistance in the brain: lessons learned from hypoxia tolerant extremophilic vertebrates

VR Garbarino, ME Orr, KA Rodriguez… - Archives of biochemistry …, 2015 - Elsevier
Abstract The Oxidative Stress Theory of Aging has had tremendous impact in research
involving aging and age-associated diseases including those that affect the nervous system …

Treadmill exercise prevents learning and memory impairment in Alzheimer's disease-like pathology

AT Dao, MA Zagaar, AT Levine, S Salim… - Current Alzheimer …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by
progressive memory loss. In contrast, accumulating evidence suggests a neuroprotective …

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox

FM Cordova, AS Aguiar, TV Peres, MW Lopes… - Archives of …, 2013 - Springer
While manganese (Mn) is essential for proper central nervous system (CNS) development,
excessive Mn exposure may lead to neurotoxicity. Mn preferentially accumulates in the …