Reviewing the mechanisms of natural product-drug interactions involving efflux transporters and metabolic enzymes

C Feltrin, CMO Simões - Chemico-biological interactions, 2019 - Elsevier
Abstract The World Health Organization (WHO) and other worldwide health agencies have
recently taken initiatives to encourage the use of traditional medicine and/or complementary …

Effects of standardized medicinal plant extracts on drug metabolism mediated by CYP3A4 and CYP2D6 enzymes

C Feltrin, IV Farias, LP Sandjo… - Chemical Research …, 2020 - ACS Publications
The use of medicinal plants concomitantly with conventional drugs can result in herb–drug
interactions that cause fluctuations in drug bioavailability and consequent therapeutic failure …

Technology Readiness Level Roadmap for Developing Innovative Herbal Medicinal Products

E Pagani, CD Ropke, CM Soares, SAC Perez… - Pharmaceuticals, 2024 - mdpi.com
Despite the vast global botanical diversity, the pharmaceutical development of herbal
medicinal products (HMPs) remains underexploited. Of over 370,000 described plant …

In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity

ALDA Mazzari, MG Lacerda, FA Milton… - Frontiers in …, 2022 - frontiersin.org
Many medicinal plants species from European-such as Artemisia absinthium, Equisetum
arvense, Lamium album, Malva sylvestris, Morus nigra, Passiflora incarnata, Frangula …

[PDF][PDF] Fitovigilância: avaliação das interações e reações adversas de fitoterápicos no mercado

APDS Roxo, EV Macedo, SC Mourão… - Vigilância Sanitária em …, 2022 - redalyc.org
Introdução: O uso de plantas medicinais como insumos farmacêuticos ativos vegetais
(IFAV), bem como o uso de fitoterápicos e suas associações com outros medicamentos …

[图书][B] Биофлавоноиды в коррекции хронического низкоградиентного воспаления

ИА Гольдина, ЕВ Маркова, КВ Гайдуль - 2021 - elibrary.ru
В монографии на основании данных современной литературы и результатов
оригинальных исследований авторов охарактеризованы основные …

In vitro effects of selected medicinal plants shortlisted for clinical use in the Brazilian public health system in CYP3A4 mRNA gene expression, glutathione levels and P …

AL Dias Araujo Mazzari - 2017 - discovery.ucl.ac.uk
The Brazilian Unified Public Health System (SUS) shortlisted various plant species of
interest (RENISUS) for future clinical use. However, very little is known about their effects on …

[PDF][PDF] Herbal medicines in Brazil: mapping the preclinical profile of the RENISUS plants and its regulatory impact

ALDA Mazzari, M Lacerda, F Milton, D Silveira… - 2019 - researchgate.net
The Brazilian Unified Public Health System (SUS) produced a list of 71 plant species of
interest (RENISUS), which could be made available to the population in the future. Although …

[PDF][PDF] Interactions between Acetaminophen and Phytotherapies: Overview for the Rational Use of Phytotherapics

JS Ribeiro, JA Saavedra, LT Nunes… - Journal of Natural …, 2018 - academia.edu
Paracetamol is the most used non-opioid analgesic in the world, and it is used to relieve
mild to moderate pain. On the other hand, phytotherapy is the use of plants or herbal …

Herbal medicines in Brazil: towards a preclinical profile of the RENISUS plants

The Brazilian Unified Public Health System (SUS) produced a list of 71 plant species of
interest (RENISUS), which could be made available to the population in the future. Although …