Biomarkers Associated With Leishmania infantum Exposure, Infection, and Disease in Dogs

C Maia, L Campino - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Canine leishmaniosis (CanL) is a vector-borne disease caused by the protozoan
Leishmania (Leishmania) infantum species [syn. L.(L.) infantum chagasi species in the …

Insights on adaptive and innate immunity in canine leishmaniosis

S Hosein, DP Blake, L Solano-Gallego - Parasitology, 2017 - cambridge.org
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a
systemic disease, which can present with variable clinical signs, and clinicopathological …

Neurological manifestations in dogs naturally infected by Leishmania infantum: descriptions of 10 cases and a review of the literature

AP Giannuzzi, M Ricciardi… - Journal of Small …, 2017 - Wiley Online Library
In order to evaluate possible nervous system involvement in canine leishmaniasis,
retrospective evaluation of all medical records of leishmaniotic dogs exhibiting neurological …

Lymphocytic hypophysitis in dogs infected with Leishmania spp.

ED Frigerio, CC Guizelini, GG Jussiani… - Frontiers in Veterinary …, 2023 - frontiersin.org
Background Morphological involvement of endocrine glands, such as the pituitary gland,
remain uninvestigated in dogs with canine visceral leishmaniasis. Therefore, this study …

Neurological disease in human and canine leishmaniasis–clinical features and immunopathogenesis

CSF Maia, MC Monteiro, EC Gavioli… - Parasite …, 2015 - Wiley Online Library
Leishmaniasis is a vectorborne disease caused by Leishmania protozoa, which is a major
health problem and a neglected disease common in many regions of the world. Leishmania …

Novel markers of inflammatory response and hepatic dysfunction in canine leishmaniasis

AA Tonin, AMC Calado, NB Bottari… - … and infectious diseases, 2016 - Elsevier
Dogs are the main host of Leishmania infantum, and the clinical presentation may range
from asymptomatic to systemic manifestations. The immune mechanisms in infected, but …

Toll-like receptors and cytokines in the brain and in spleen of dogs with visceral leishmaniosis

FG Grano, JES Silva, GD Melo, MS de Souza… - Veterinary …, 2018 - Elsevier
Visceral leishmaniosis (VL) is a multisystem disease that affects domestic dogs and can
have several clinical manifestations, including some rare reports of neurological clinical …

Dog skin parasite load, TLR‐2, IL‐10 and TNF‐α expression and infectiousness

DCM Pereira‐Fonseca, FM Oliveira‐Rovai… - Parasite …, 2017 - Wiley Online Library
Visceral leishmaniosis is a zoonotic disease that is transmitted by Lutzomyia longipalpis
sandflies. Dogs are the main peri‐urban reservoir of the disease, and progression of canine …

Leishmania infection and neuroinflammation: Specific chemokine profile and absence of parasites in the brain of naturally-infected dogs

GD Melo, JES Silva, FG Grano, MS Souza… - Journal of …, 2015 - Elsevier
Visceral leishmaniasis is a chronic disease caused by Leishmania infantum. We aimed to
detect the parasite in the brain of fifteen naturally-infected dogs using in situ hybridization …

Compartmentalized gene expression of toll‐like receptors 2, 4 and 9 in the brain and peripheral lymphoid organs during canine visceral leishmaniasis

GD Melo, JES Silva, FG Grano, CG Homem… - Parasite …, 2014 - Wiley Online Library
Visceral leishmaniasis is an important parasitic disease that affects humans and animals.
The response against the protozoan involves the interaction of both innate and adaptive …