It is now possible to grow DC-like cells in culture17-21 and extensive cell membrane
processes that are acquired late the first monoclonal antibodies (MoAbs) 22, 23 that react …

Tuberculosis is a major cause of death around the world, with most of the 1.5 million deaths
per year attributable to the disease occurring in developing countries. This disease is …

Phagocytosis provides innate immune cells with a mechanism to take up and destroy
pathogenic bacteria, apoptotic cells and other large particles. In some cases, however …

Most people infected with Mycobacterium tuberculosis contain the initial infection and
develop latent tuberculosis. This state is characterised by evidence of an immune response …

I n this issue, Sallusto et al.(1) report that dendritic cells. can vigorously internalize solutes by
macropinocytosis, delivering these to MHC class II-rich vesicles (MIIVs). In the most familiar …

Dendritic cells derived in vitro from monocytes are known to be poor phagocytes. Here we
show that, unlike macrophages, monocyte‐derived dendritic cells indeed fail to take up …

Candida albicans is a component of the normal flora of the alimentary tract and also is found
on the mucocutaneous membranes of the healthy host. Candida is the leading cause of …

Publisher Summary The complex contest between bacteria and the mammalian host follows
different game plans that are undertaken to ensure the survival of both the pathogen and the …

Dendritic cells (DC) are unique in their ability to initiate a primary immune response by the
presentation of soluble Ags to T cells. Recent studies have shown that DC also phagocytose …

Kenneth H. Sonnenfeld 57 ABSTRACT A method for producing proliferating cultures of
dendritic cell precursors is provided. Also provided is a method for producing mature …