Metabolism and functional effects of plant-derived omega-3 fatty acids in humans

EJ Baker, EA Miles, GC Burdge, P Yaqoob… - Progress in lipid …, 2016 - Elsevier
Alpha-linolenic acid (ALA) is an essential fatty acid and the substrate for the synthesis of
longer-chain, more unsaturated ω-3 fatty acids, eicosapentaenoic acid (EPA) …

Health effects of trans-fatty acids: experimental and observational evidence

D Mozaffarian, A Aro, WC Willett - European journal of clinical nutrition, 2009 - nature.com
Results: The effects of TFA consumption on risk factors most consistently seen in both
controlled trials and observational studies included adverse lipid effects (for example↑ low …

α-Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation

KB Kim, YA Nam, HS Kim, AW Hayes… - Food and chemical …, 2014 - Elsevier
Abstract α-Linolenic acid (ALA), a carboxylic acid with 18 carbons and three cis double
bonds, is an essential fatty acid needed for human health and can be acquired via regular …

Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements

M Plourde, SC Cunnane - Applied physiology, nutrition, and …, 2007 - cdnsciencepub.com
There is considerable interest in the potential impact of several polyunsaturated fatty acids
(PUFAs) in mitigating the significant morbidity and mortality caused by degenerative …

Dietary n-6 and n-3 fatty acid balance and cardiovascular health

V Wijendran, KC Hayes - Annu. Rev. Nutr., 2004 - annualreviews.org
▪ Abstract Epidemiological and clinical studies have established that the n-6 fatty acid,
linoleic acid (LA), and the n-3 fatty acids, linolenic acid (LNA), eicosapentaenoic acid (EPA) …

[图书][B] Eat, drink, and be healthy: the Harvard Medical School guide to healthy eating

W Willett, PJ Skerrett, EL Giovannucci - 2017 - books.google.com
In this revised and updated edition of the bestselling Eat, Drink, and Be Healthy, Dr. Walter
Willett, for twenty-five years chair of the renowned Department of Nutrition at the Harvard TH …

[HTML][HTML] Prevention of chronic disease by means of diet and lifestyle changes

WC Willett, JP Koplan, R Nugent… - … Control Priorities in …, 2006 - ncbi.nlm.nih.gov
Coronary artery disease (CAD), ischemic stroke, diabetes, and some specific cancers, which
until recently were common only in high-income countries, are now becoming the dominant …

The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid

D Rodriguez-Leyva, CMC Bassett… - Canadian Journal of …, 2010 - Elsevier
Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a
therapeutic strategy that may warrant greater research attention. The increased use of …

The Mediterranean diet: science and practice

WC Willett - Public health nutrition, 2006 - cambridge.org
ObjectiveTo provide an overview of research relevant to the Mediterranean diet.
DesignPersonal perspectives. SettingInternational. SubjectPopulations in Europe, North …

Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men

D Mozaffarian, A Ascherio, FB Hu, MJ Stampfer… - Circulation, 2005 - Am Heart Assoc
Background—Consumption of polyunsaturated fatty acids (PUFAs) may reduce coronary
heart disease (CHD) risk, but n-6 PUFAs may compete with n-3 PUFA metabolism and …