Traditional therapeutic approaches such as chemotherapy and radiation therapy have
burdened cancer patients with onerous physical and psychological challenges …

Angiogenesis, the sprouting of new blood vessels from existing vessels, is one of six known
mechanisms employed by solid tumors to recruit blood vessels necessary for their initiation …

Angiogenesis is a hallmark of cancer and is required for tumor growth and progression.
Antiangiogenic therapy has been revolutionarily developing and was approved for the …

Tumor growth and metastasis rely on tumor vascular network for the adequate supply of
oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth …

Anti-angiogenesis therapy, a promising strategy against cancer progression, is limited by
drug-resistance, which could be attributed to changes within the tumor microenvironment …

Tumours require a vascular supply to grow and can achieve this via the expression of pro-
angiogenic growth factors, including members of the vascular endothelial growth factor …

Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

Introduction The vascular endothelial growth factor A (VEGF) is the main mediator of
angiogenesis. In addition, VEGF contributes to cancer growth and metastasis directly …

Tumour cells, with stem-like properties, are highly aggressive and often show drug
resistance. Here, we reveal that integrin α v β3 serves as a marker of breast, lung and …

Pericytes are a heterogeneous population of cells located in the blood vessel wall. They
were first identified in the 19th century by Rouget, however their biological role and potential …