Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

The inability of adult mammals to recover function lost after severe spinal cord injury (SCI)
has been known for millennia and is mainly attributed to a failure of brain-derived nerve fiber …

Spinal cord ependymal cells display neural stem cell properties in vitro and generate scar-
forming astrocytes and remyelinating oligodendrocytes after injury. We report that …

Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

Background Wound healing of skin is a complicated process. Cutaneous innervation and
neurotrophic factors could participate in multiple stages of wound healing. Neurotrophic …

Spinal cord injury (SCI) is a serious neurological trauma that is challenging to treat. After
SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes …

Background Nestin is an intermediate filament first reported in neuroepithelial stem cells.
Nestin expression could be found in a variety of tissues throughout all systems of the body …

Nestin is expressed extensively in neural stem/progenitor cells during neural development,
but its expression is mainly restricted to the ependymal cells in the adult spinal cord. After …

Cytology and histology obstacles have been the main barriers to multiple tissues injury
repair. In search of the most promising treatment strategies for spinal cord injury (SCI), stem …

The proliferation and ectopic migration of neural precursor cells (NPCs) in response to
ischemic brain injury was first reported two decades ago. Since then, studies of brain injury …