The current role of MRI in differentiating multiple sclerosis from its imaging mimics

R Geraldes, O Ciccarelli, F Barkhof… - Nature Reviews …, 2018 - nature.com
MRI red flags proposed over a decade ago by the European Magnetic Resonance Network
in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS) …

[HTML][HTML] Imaging perivascular space structure and function using brain MRI

G Barisano, KM Lynch, F Sibilia, H Lan, NC Shih… - Neuroimage, 2022 - Elsevier
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

Multi-channel multi-scale fully convolutional network for 3D perivascular spaces segmentation in 7T MR images

C Lian, J Zhang, M Liu, X Zong, SC Hung, W Lin… - Medical image …, 2018 - Elsevier
Accurate segmentation of perivascular spaces (PVSs) is an important step for quantitative
study of PVS morphology. However, since PVSs are the thin tubular structures with relatively …

[HTML][HTML] Fluid dynamics in aging-related dementias

TM Bah, DA Siler, AH Ibrahim, JS Cetas… - Neurobiology of …, 2023 - Elsevier
Recent human and animal model experimental studies revealed novel pathways for fluid
movement, immune cell trafficking and metabolic waste clearance in CNS. These studies …

Perivascular unit: This must be the place. The anatomical crossroad between the immune, vascular and nervous system

F Troili, V Cipollini, M Moci, E Morena… - Frontiers in …, 2020 - frontiersin.org
Most neurological disorders seemingly have heterogenous pathogenesis, with overlapping
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …

Improved detection of cortical MS lesions with phase-sensitive inversion recovery MRI

V Sethi, TA Yousry, N Muhlert, M Ron… - Journal of Neurology …, 2012 - jnnp.bmj.com
Objective Cortical grey matter lesions are common in multiple sclerosis (MS), but usually not
seen on MRI. The authors compared the performance of double inversion recovery (DIR …

[HTML][HTML] Brain perivascular space imaging across the human lifespan

KM Lynch, F Sepehrband, AW Toga, J Choupan - Neuroimage, 2023 - Elsevier
Enlarged perivascular spaces (PVS) are considered a biomarker for vascular pathology and
are observed in normal aging and neurological conditions; however, research on the role of …

Enlarged perivascular spaces in multiple sclerosis on magnetic resonance imaging: a systematic review and meta-analysis

T Granberg, T Moridi, JS Brand, S Neumann… - Journal of …, 2020 - Springer
Background Perivascular spaces can become detectable on magnetic resonance imaging
(MRI) upon enlargement, referred to as enlarged perivascular spaces (EPVS) or Virchow …

[HTML][HTML] Ethnic disparities in the epidemiological and clinical characteristics of multiple sclerosis

G Mallawaarachchi, DJ Rog, J Das - Multiple Sclerosis and Related …, 2024 - Elsevier
Abstract Background Multiple Sclerosis (MS) is a neuroinflammatory disorder which affects
2.8 million people world-wide. A growing body of evidence shows ethnic disparities in MS …

Dilated Virchow-Robin spaces are a marker for arterial disease in multiple sclerosis

BV Ineichen, C Cananau, M Plattén, R Ouellette… - …, 2023 - thelancet.com
Summary Background Virchow-Robin spaces (VRS) have been associated with
neurodegeneration and neuroinflammation. However, it remains uncertain to what degree …