Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity
In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …
cause of numerous health complications and increased mortality. Being a complex and …
Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance
AR Aroor, S McKarns, VG DeMarco, G Jia, JR Sowers - Metabolism, 2013 - Elsevier
Insulin resistance is a hallmark of obesity, the cardiorenal metabolic syndrome and type 2
diabetes mellitus (T2DM). The progression of insulin resistance increases the risk for …
diabetes mellitus (T2DM). The progression of insulin resistance increases the risk for …
The association between breastfeeding and childhood obesity: a meta-analysis
Background The increase in childhood obesity is a serious public health concern. Several
studies have indicated that breastfed children have a lower risk of childhood obesity than …
studies have indicated that breastfed children have a lower risk of childhood obesity than …
Pediatric obesity. An introduction
JA Yanovski - Appetite, 2015 - Elsevier
The prevalence of child and adolescent obesity in the United States increased dramatically
between 1970 and 2000, and there are few indications that the rates of childhood obesity …
between 1970 and 2000, and there are few indications that the rates of childhood obesity …
Dietary carbohydrates: Pathogenesis and potential therapeutic targets to obesity‐associated metabolic syndrome
Metabolic syndrome (MetS) is a common feature in obesity, comprising a cluster of
abnormalities including abdominal fat accumulation, hyperglycemia, hyperinsulinemia …
abnormalities including abdominal fat accumulation, hyperglycemia, hyperinsulinemia …
Effect of long-term high-fat diet intake on peripheral insulin sensibility, blood pressure, and renal function in female rats
NAV Roza, LF Possignolo, AC Palanch… - Food & nutrition …, 2016 - Taylor & Francis
Background This study determines whether 8-week high-fat diet (HFD) consumption alters
insulin sensitivity, kidney function, and blood pressure (BP) in female rats when compared …
insulin sensitivity, kidney function, and blood pressure (BP) in female rats when compared …
Investigation of the interaction between Genetic Risk Score (GRS) and fatty acid quality indices on mental health among overweight and obese women
Background & aims Mental disorders are associated with dietary fatty acids and genome-
wide association studies have found multiple risk loci robustly related to depression, anxiety …
wide association studies have found multiple risk loci robustly related to depression, anxiety …
Leptin in human milk—one of the key regulators of nutritional programming
E Sinkiewicz-Darol, I Adamczyk, K Łubiech, G Pilarska… - Molecules, 2022 - mdpi.com
Breast milk is the optimal food for infants and toddlers, providing basic nutrients. It is also a
source of many biologically active substances. Among them are hormones responsible for …
source of many biologically active substances. Among them are hormones responsible for …
Metabolomic signatures for the effects of weight loss interventions on severe obesity in children and adolescents
Childhood obesity has increased worldwide, and many clinical and public interventions
have attempted to reduce morbidity. We aimed to determine the metabolomic signatures …
have attempted to reduce morbidity. We aimed to determine the metabolomic signatures …
Childhood obesity and the metabolic syndrome
S Owens, R Galloway - Current atherosclerosis reports, 2014 - Springer
Although research published during the past year suggests the prevalence of childhood
obesity in the USA may have plateaued, it remains unacceptably high and places large …
obesity in the USA may have plateaued, it remains unacceptably high and places large …