Recent advances in high intensity focused ultrasound (HIFU), which was developed in the
1940s as a viable thermal tissue ablation approach, have increased its popularity. In clinics …

In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within
the body to locally affect the targeted site without damaging intervening tissues. The most …

Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …

Histotripsy is a therapy that focuses short-duration, high-amplitude pulses of ultrasound to
incite a localized cavitation cloud that mechanically breaks down tissue. To investigate the …

Acoustic cavitation has been shown to play a key role in a wide array of novel therapeutic
ultrasound applications. This paper presents a brief discussion of the physics of thermally …

Purpose: The optimal minimally invasive treatment for small renal masses continues to
evolve. Current ablative technologies rely on thermal mechanisms for tissue destruction …

Clinically available thrombolysis techniques are limited by either slow reperfusion (drugs) or
invasiveness (catheters) and carry significant risks of bleeding. In this study, the feasibility of …

Therapy methods using pulsed cavitational ultrasound therapy can include the
subprocesses of initiation, maintenance, therapy, and feedback of the histotripsy process …

Histotripsy is an ultrasound ablation method that depends on the initiation of a cavitation
bubble cloud to fractionate soft tissue. Previous work has indicated that a cavitation cloud …

Focused ultrasound offers a non-invasive way of depositing acoustic energy deep into the
body, which can be harnessed for a broad spectrum of therapeutic purposes, including …