Background The aim of this study was to estimate the prevalence of pneumonia and
secondary bacterial infections during the pandemic of influenza A (H1N1) pdm09. Methods …

2018 marks the 100-year anniversary of the 1918 influenza pandemic, which killed~ 50
million people worldwide. The severity of this pandemic resulted from a complex interplay …

These clinical practice guidelines are an update of the guidelines published by the
Infectious Diseases Society of America (IDSA) in 2009, prior to the 2009 H1N1 influenza …

When facing an acute viral infection, our immune systems need to function with finite
precision to enable the elimination of the pathogen, whilst protecting our bodies from …

The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife
market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led …

Influenza viruses are still a serious threat to human health. Cytokines are essential for cell-to-
cell communication and viral clearance in the immune system, but excessive cytokines can …

Background: Which virological factors mediate overdispersion in the transmissibility of
emerging viruses remains a long-standing question in infectious disease epidemiology …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells following
binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 …

COVID-19 pathogenesis is associated with an exaggerated immune response. However, the
specific cellular mediators and inflammatory components driving diverse clinical disease …

Background Human infection with avian influenza A H7N9 virus emerged in eastern China
in February, 2013, and has been associated with exposure to poultry. We report the clinical …