The therapeutic potential of apigenin

B Salehi, A Venditti, M Sharifi-Rad, D Kręgiel… - International journal of …, 2019 - mdpi.com
Several plant bioactive compounds have exhibited functional activities that suggest they
could play a remarkable role in preventing a wide range of chronic diseases. The largest …

Flavonoids: Overview of biosynthesis, biological activity, and current extraction techniques

S Liga, C Paul, F Péter - Plants, 2023 - mdpi.com
Recently, increased attention has been paid to natural sources as raw materials for the
development of new added-value products. Flavonoids are a large family of polyphenols …

Parthenolide promotes the repair of spinal cord injury by modulating M1/M2 polarization via the NF-κB and STAT 1/3 signaling pathway

T Gaojian, Q Dingfei, L Linwei, W Xiaowei… - Cell death …, 2020 - nature.com
Spinal cord injury (SCI) is a severe neurological disease; however, there is no effective
treatment for spinal cord injury. Neuroinflammation involves the activation of resident …

Modern techniques for flavonoid extraction—to optimize or not to optimize?

A Jurinjak Tušek, D Šamec, A Šalić - Applied Sciences, 2022 - mdpi.com
Flavonoids, specialized metabolites found in plants, have a number of beneficial properties
and are important for maintaining good health. Efficient extraction methods are required to …

Efficient enrichment of total flavonoids from Pteris ensiformis Burm. extracts by macroporous adsorption resins and in vitro evaluation of antioxidant and …

M Hou, W Hu, Z Xiu, Y Shi, K Hao, D Cao… - … of Chromatography B, 2020 - Elsevier
The aim of this work is to develop an efficient and economical method for the enrichment of
total flavonoids from Pteris ensiformis Burm. extracts. Resin screening, adsorption kinetics …

LC/MS/MS and GC/MS/MS metabolic profiling of Leontodon hispidulus, in vitro and in silico anticancer activity evaluation targeting hexokinase 2 enzyme

NM Abd-El-Aziz, MS Hifnawy, RA Lotfy, IY Younis - Scientific Reports, 2024 - nature.com
Leontodon hispidulus Boiss is a wild annual plant growing in Egypt. The present study aims
for the first time, to evaluate the phytochemical profile of the main secondary metabolites of …

[HTML][HTML] Isolation and quantification of diarylheptanoids from European hornbeam (Carpinus betulus L.) and HPLC-ESI-MS/MS characterization of its antioxidative …

CA Felegyi-Tóth, Z Garádi, A Darcsi, O Csernák… - … of Pharmaceutical and …, 2022 - Elsevier
Detailed polyphenol profiling of European hornbeam (Carpinus betulus L.) bark, leaf, male
and female catkin extracts was performed by high-performance liquid chromatography …

Modern and traditional extraction techniques affect chemical composition and bioactivity of Tanacetum parthenium (L.) Sch. Bip

G Zengin, A Cvetanović, U Gašić, A Stupar… - Industrial Crops and …, 2020 - Elsevier
Abstract Tanacetum parthenium (L.) Sch. Bip (TP), a flowering plant, is famous in traditional
medicine to prevent migraine and headache. However, there is currently a dearth of studies …

Potential Anti-Acetylcholinesterase Activity of Cassia timorensis DC.

NAN Azman, MB Alhawarri, MSA Rawa, R Dianita… - Molecules, 2020 - mdpi.com
Seventeen methanol extracts from different plant parts of five different Cassia species,
including C. timorensis, C. grandis, C. fistula, C. spectabilis, and C. alata were screened …

[HTML][HTML] Micheliolide attenuates neuroinflammation to improve cognitive impairment of Alzheimer's disease by inhibiting NF-κB and PI3K/Akt signaling pathways

G Yang, Y Hu, X Qin, J Sun, Z Miao, L Wang, Z Ke… - Heliyon, 2023 - cell.com
Inflammatory reaction in the brain activates glial cells, and over-activated glial cells secrete
inflammatory mediators, which aggravates the inflammatory response in the brain and …