Current understanding of the mechanism of water oxidation in photosystem II and its relation to XFEL data

N Cox, DA Pantazis, W Lubitz - Annual review of biochemistry, 2020 - annualreviews.org
The investigation of water oxidation in photosynthesis has remained a central topic in
biochemical research for the last few decades due to the importance of this catalytic process …

Water oxidation in oxygenic photosynthesis studied by magnetic resonance techniques

W Lubitz, DA Pantazis, N Cox - FEBS letters, 2023 - Wiley Online Library
The understanding of light‐induced biological water oxidation in oxygenic photosynthesis is
of great importance both for biology and (bio) technological applications. The chemically …

High-resolution cryo-electron microscopy structure of photosystem II from the mesophilic cyanobacterium, Synechocystis sp. PCC 6803

CJ Gisriel, J Wang, J Liu, DA Flesher… - Proceedings of the …, 2022 - National Acad Sciences
Photosystem II (PSII) enables global-scale, light-driven water oxidation. Genetic
manipulation of PSII from the mesophilic cyanobacterium Synechocystis sp. PCC 6803 has …

Functional water networks in fully hydrated photosystem II

A Sirohiwal, DA Pantazis - Journal of the American Chemical …, 2022 - ACS Publications
Water channels and networks within photosystem II (PSII) of oxygenic photosynthesis are
critical for enzyme structure and function. They control substrate delivery to the oxygen …

[HTML][HTML] Structural dynamics in the water and proton channels of photosystem II during the S2 to S3 transition

R Hussein, M Ibrahim, A Bhowmick, PS Simon… - Nature …, 2021 - nature.com
Light-driven oxidation of water to molecular oxygen is catalyzed by the oxygen-evolving
complex (OEC) in Photosystem II (PS II). This multi-electron, multi-proton catalysis requires …

Does serial femtosecond crystallography depict state-specific catalytic intermediates of the oxygen-evolving complex?

M Drosou, G Comas-Vilà, F Neese… - Journal of the …, 2023 - ACS Publications
Recent advances in serial femtosecond crystallography (SFX) of photosystem II (PSII),
enabled by X-ray free electron lasers (XFEL), provided the first geometric models of distinct …

[HTML][HTML] Proton exit pathways surrounding the oxygen evolving complex of photosystem II

D Kaur, Y Zhang, KM Reiss, M Mandal… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Photosystem II allows water to be the primary electron source for the photosynthetic electron
transfer chain. Water is oxidized to dioxygen at the Oxygen Evolving Complex (OEC), a Mn 4 …

[HTML][HTML] Successes, challenges, and opportunities for quantum chemistry in understanding metalloenzymes for solar fuels research

M Orio, DA Pantazis - Chemical Communications, 2021 - pubs.rsc.org
Quantum chemical approaches today are a powerful tool to study the properties and
reactivity of metalloenzymes. In the field of solar fuels research these involve predominantly …

Occupancy Analysis of Water Molecules inside Channels within 25 Å Radius of the Oxygen-Evolving Center of Photosystem II in Molecular Dynamics Simulations

D Kaur, K Reiss, J Wang, VS Batista… - The Journal of …, 2024 - ACS Publications
At room temperature and neutral pH, the oxygen-evolving center (OEC) of photosystem II
(PSII) catalyzes water oxidation. During this process, oxygen is released from the OEC …

Proton and Water Transfer Pathways in the S2 → S3 Transition of the Water-Oxidizing Complex in Photosystem II: Time-Resolved Infrared Analysis of the Effects of D1-N298A Mutation …

Y Okamoto, Y Shimada, R Nagao… - The Journal of Physical …, 2021 - ACS Publications
Photosynthetic water oxidation is performed through a light-driven cycle of five intermediates
(S0–S4 states) in photosystem II (PSII). The S2→ S3 transition, which involves concerted …