Applications and limitations of dendrimers in biomedicine
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
New insights into mechanisms of cisplatin resistance: from tumor cell to microenvironment
SH Chen, JY Chang - International journal of molecular sciences, 2019 - mdpi.com
Although cisplatin has been a pivotal chemotherapy drug in treating patients with various
types of cancer for decades, drug resistance has been a major clinical impediment. In …
types of cancer for decades, drug resistance has been a major clinical impediment. In …
Characterization of cisplatin-loaded chitosan nanoparticles and rituximab-linked surfaces as target-specific injectable nano-formulations for combating cancer
The present study was carried out to develop cisplatin-loaded chitosan nanoparticles
(CCNP) and cisplatin-loaded chitosan nanoparticle surface linked to rituximab (mAbCCNP) …
(CCNP) and cisplatin-loaded chitosan nanoparticle surface linked to rituximab (mAbCCNP) …
A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer
M Goldberg, A Manzi, A Birdi, B Laporte… - Nature …, 2022 - nature.com
Despite therapeutic advancements, oral cavity squamous cell carcinoma (OCSCC) remains
a difficult disease to treat. Systemic platinum-based chemotherapy often leads to dose …
a difficult disease to treat. Systemic platinum-based chemotherapy often leads to dose …
Can cisplatin therapy be improved? Pathways that can be targeted
Cisplatin (cis-diamminedichloroplatinum (II)) is the oldest known chemotherapeutic agent.
Since the identification of its anti-tumour activity, it earned a remarkable place as a treatment …
Since the identification of its anti-tumour activity, it earned a remarkable place as a treatment …
Efficient, enzyme responsive and tumor receptor targeting gelatin nanoparticles decorated with concanavalin-A for site-specific and controlled drug delivery for cancer …
The tumor targeting and stimuli responsiveness behavior of intelligent drug delivery systems
imparts effective therapeutic delivery and decreases the toxicity of conventional …
imparts effective therapeutic delivery and decreases the toxicity of conventional …
[HTML][HTML] Surface engineered metal-organic frameworks as active targeting nanomedicines for mono-and multi-therapy
The precision tenability of metal-organic frameworks (MOFs) enables the efficient
encapsulation of a wide variety of small-molecule pharmaceuticals and macromolecular …
encapsulation of a wide variety of small-molecule pharmaceuticals and macromolecular …
Recent advances in the treatment of bone metastases and primary bone tumors: An up-to-date review
AE Bădilă, DM Rădulescu, AG Niculescu… - Cancers, 2021 - mdpi.com
Simple Summary Bone represents a common metastatic site for patients with advanced
cancers while also being associated with rare but challenging primary tumors. As the …
cancers while also being associated with rare but challenging primary tumors. As the …
Preparation and characterization of PLGA-PEG-PLGA polymeric nanoparticles for co-delivery of 5-Fluorouracil and Chrysin
Despite significant advances in cancer therapy, chemotherapeutic agents are still the main
types of drugs used to treat cancer patients. 5-Fluorouracil (5-FU) is the first-line treatment in …
types of drugs used to treat cancer patients. 5-Fluorouracil (5-FU) is the first-line treatment in …
Implantable smart hyperthermia nanofibers for cancer therapy: Challenges and opportunities
Nanofibers (NFs) with practical drug‐loading capacities, high stability, and controllable
release have caught the attention of investigators due to their potential applications in on …
release have caught the attention of investigators due to their potential applications in on …