Bacteriophage T4 genome

ES Miller, E Kutter, G Mosig, F Arisaka… - Microbiology and …, 2003 - Am Soc Microbiol
Phage T4 has provided countless contributions to the paradigms of genetics and
biochemistry. Its complete genome sequence of 168,903 bp encodes about 300 gene …

Evolutionary dynamics between phages and bacteria as a possible approach for designing effective phage therapies against antibiotic-resistant bacteria

M Hasan, J Ahn - Antibiotics, 2022 - mdpi.com
With the increasing global threat of antibiotic resistance, there is an urgent need to develop
new effective therapies to tackle antibiotic-resistant bacterial infections. Bacteriophage …

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

J Summers, WS Mason - Cell, 1982 - cell.com
Duck hepatitis B virus, a DNA virus closely related to human hepatitis B virus, was studied in
infected duck liver. Subviral particles resembling the viral nucleocapsid cores were isolated …

Efficient octopine Ti plasmid-derived vectors for Agrobacterium-mediated gene transfer to plants

R Deblaere, B Bytebier, H De Greve… - Nucleic acids …, 1985 - academic.oup.com
A two-component cloning system to transfer foreign DNA into plants was derived from the
octopine Ti plasmid pTiB6S3. pGV2260 is a non-oncogenic Ti plasmid from which the T …

Ti plasmid vector for the introduction of DNA into plant cells without alteration of their normal regeneration capacity

P Zambryski, H Joos, C Genetello, J Leemans… - The EMBO …, 1983 - embopress.org
A Ti plasmid mutant was constructed in which all the on‐cogenic functions of the T‐DNA
have been deleted and replaced by pBR322. This Ti plasmid, pGV3850, still mediates …

Isolation of a putative phospholipase C gene of Drosophila, norpA, and its role in phototransduction

BT Bloomquist, RD Shortridge, S Schneuwly… - Cell, 1988 - cell.com
Severe norpA mutations in Drosophila eliminate the photoreceptor potential and render the
fly completely blind. Recent biochemical analyses have shown that norpA mutants lack …

Mechanism of met oncogene activation

M Park, M Dean, CS Cooper, M Schmidt, SJ O'Brien… - Cell, 1986 - cell.com
The met oncogene activated in vitro by treatment of a human osteogenic sarcoma (HOS) cell
line with N-methyl-N'-nitronitrosoguanidine(MNNG) is related to the tyrosine kinase gene …

Chimeric genes as dominant selectable markers in plant cells

L Herrera‐Estrella, M De Block, E Messens… - The EMBO …, 1983 - embopress.org
Opine synthases are enzymes produced in dicotyledonous plants as the result of a natural
gene transfer phenomenon. Agrobacteria contain Ti plasmids that direct the transfer, stable …

A method for isolation of intact, translationally active ribonucleic acid

GUY Cathala, JF SAVOURET, B Mendez, BL West… - Dna, 1983 - liebertpub.com
ABSTRACT A method for isolation of large, translationally active RNA species is presented.
The procedure involves homogenization of cells or tissues in 5 m guanidine …

Extraordinary stability of enzymes dried in trehalose: simplified molecular biology

C Colaco, S Sen, M Thangavelu, S Pinder, B Roser - Bio/technology, 1992 - nature.com
We show that extremely fragile biomolecules such as DNA restriction and modifying
enzymes can be dried in vitro in the presence of trehalose with no loss of activity, even after …