Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

In skeletal muscle, growth of capillaries is an important adaptation to exercise training that
secures adequate diffusion capacity for oxygen and nutrients even at high‐intensity exercise …

Muscle VEGF expression is upregulated by exercise. Whether this VEGF response is
regulated by transcription and/or post-transcriptional mechanisms is unknown. Hypoxia may …

New Findings What is the topic of this review? The role of hypoxia and, more specifically, the
role of the hypoxia‐sensitive transcription factor hypoxia‐inducible factor‐1 (HIF‐1) in …

Exercise-induced skeletal muscle angiogenesis is a well-known physiological adaptation
that occurs in humans in response to exercise training and can lead to endurance …

Background and Purpose. Dry needling is an effective therapy for the treatment of pain
associated with myofascial trigger point (MTrP). However, the biochemical effects of dry …

Peripheral arterial disease (PAD) is a common vascular disease that reduces blood flow
capacity to the legs of patients. PAD leads to exercise intolerance that can progress in …

Nitric oxide can interact with a wide range of proteins including many that are involved in
metabolism. In this review we have summarized the effects of NO on glycolysis, fatty acid …

Several cytokine families have roles in the development, maintenance, and remodeling of
the microcirculation. Of these, the vascular endothelial growth factor (VEGF) family is one of …

The aims of this study were 1) to characterize changes in matrix metalloproteinase (MMP),
endostatin, and vascular endothelial growth factor (VEGF)-A expression in skeletal muscle …