Clustered miRNAs and their role in biological functions and diseases

SP Kabekkodu, V Shukla, VK Varghese… - Biological …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Non-coding RNAs in necroptosis, pyroptosis and ferroptosis in cancer metastasis

Y Liu, Q Chen, Y Zhu, T Wang, L Ye, L Han, Z Yao… - Cell death …, 2021 - nature.com
Distant metastasis is the main cause of death for cancer patients. Recently, the newly
discovered programmed cell death includes necroptosis, pyroptosis, and ferroptosis, which …

Graph convolutional network and convolutional neural network based method for predicting lncRNA-disease associations

P Xuan, S Pan, T Zhang, Y Liu, H Sun - Cells, 2019 - mdpi.com
Aberrant expressions of long non-coding RNAs (lncRNAs) are often associated with
diseases and identification of disease-related lncRNAs is helpful for elucidating complex …

[HTML][HTML] Atherosclerosis and cancer; a resemblance with far-reaching implications

JV Tapia-Vieyra, B Delgado-Coello… - Archives of medical …, 2017 - Elsevier
Atherosclerosis and cancer are chronic diseases considered two of the main causes of
death all over the world. Taking into account that both diseases are multifactorial, they share …

Epidemiologic study of gastric cancer in Iran: a systematic review

K Kalan Farmanfarma, N Mahdavifar… - Clinical and …, 2020 - Taylor & Francis
Background Gastric cancer (GC) is one of the most common cancers in Iran. Knowledge of
the epidemiology of the disease is essential in planning for prevention. So this study aimed …

A random forest based computational model for predicting novel lncRNA-disease associations

D Yao, X Zhan, X Zhan, CK Kwoh, P Li, J Wang - BMC bioinformatics, 2020 - Springer
Background Accumulated evidence shows that the abnormal regulation of long non-coding
RNA (lncRNA) is associated with various human diseases. Accurately identifying disease …

Cluster miRNAs and cancer: Diagnostic, prognostic and therapeutic opportunities

SP Kabekkodu, V Shukla, VK Varghese… - Wiley …, 2020 - Wiley Online Library
MiRNAs are class of noncoding RNA important for gene expression regulation in many
plants, animals and viruses. MiRNA clusters contain a set of two or more miRNA encoding …

Dual convolutional neural networks with attention mechanisms based method for predicting disease-related lncRNA genes

P Xuan, Y Cao, T Zhang, R Kong, Z Zhang - Frontiers in genetics, 2019 - frontiersin.org
A lot of studies indicated that aberrant expression of long non-coding RNA genes (lncRNAs)
is closely related to human diseases. Identifying disease-related lncRNAs (disease …

KHDRBS3 promotes paclitaxel resistance and induces glycolysis through modulated MIR17HG/CLDN6 signaling in epithelial ovarian cancer

X Wu, L Qiu, H Feng, H Zhang, H Yu, Y Du, H Wu… - Life Sciences, 2022 - Elsevier
Paclitaxel (PTX) resistance contributes to mortality in epithelial ovarian cancer (EOC).
Aerobic glycolysis is elevated in the tumor environment and may influence resistance to PTX …

MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma

SJ Mai, RW Xiao, L Shi, XM Zhou, T Yang… - Cell Death & …, 2019 - nature.com
Abstract miR-18a has been reported to be upregulated in nasopharyngeal carcinoma (NPC)
tissues by microarray assays. However, the roles and the underlying mechanisms of miR …