Envelope stress responses: balancing damage repair and toxicity

AM Mitchell, TJ Silhavy - Nature Reviews Microbiology, 2019 - nature.com
The Gram-negative envelope is a complex structure that consists of the inner membrane, the
periplasm, peptidoglycan and the outer membrane, and protects the bacterial cell from the …

Themes and variations in prokaryotic cell division

W Margolin - FEMS microbiology reviews, 2000 - academic.oup.com
Perhaps the biggest single task facing a bacterial cell is to divide into daughter cells that
contain the normal complement of chromosomes. Recent technical and conceptual …

Characterization of a two-component regulatory system from Acinetobacter baumannii that controls biofilm formation and cellular morphology

AP Tomaras, MJ Flagler, CW Dorsey… - …, 2008 - microbiologyresearch.org
Acinetobacter baumannii forms biofilms on abiotic surfaces, a phenotype that may explain its
ability to survive in nosocomial environments and to cause device-related infections in …

Characterization of the Cpx Regulon in Escherichia coli Strain MC4100

NL Price, TL Raivio - Journal of bacteriology, 2009 - Am Soc Microbiol
The Cpx two-component signal transduction pathway of Escherichia coli mediates
adaptation to envelope protein misfolding. However, there is experimental evidence that at …

Exploiting the fitness cost of metallo-β-lactamase expression can overcome antibiotic resistance in bacterial pathogens

MM Tu, LA Carfrae, K Rachwalski, S French… - Nature …, 2025 - nature.com
Carbapenems are last-resort antibiotics for treating bacterial infections. The widespread
acquisition of metallo-β-lactamases, such as VIM-2, contributes to the emergence of …

Genome-wide profiling of promoter recognition by the two-component response regulator CpxR-P in Escherichia coli

P De Wulf, AM McGuire, X Liu, ECC Lin - Journal of Biological Chemistry, 2002 - ASBMB
In Escherichia coli, the two-component Cpx system comprising the CpxA sensor kinase and
the CpxR response regulator modulates gene expression in response to a variety of …

Bacterial cell division

LL Rothfield, S Justice… - Annual review of genetics, 1999 - annualreviews.org
▪ Abstract Formation of the bacterial division septum is catalyzed by a number of essential
proteins that assemble into a ring structure at the future division site. Assembly of proteins …

The CpxRA Signal Transduction System ofEscherichia coli: Growth-Related Autoactivation and Control of Unanticipated Target Operons

P De Wulf, O Kwon, ECC Lin - Journal of bacteriology, 1999 - Am Soc Microbiol
ABSTRACT In Escherichia coli, the CpxRA two-component signal transduction system
senses and responds to aggregated and misfolded proteins in the bacterial envelope. We …

Fine-tuning of the Cpx envelope stress response is required for cell wall homeostasis in Escherichia coli

A Delhaye, JF Collet, G Laloux - MBio, 2016 - Am Soc Microbiol
The envelope of Gram-negative bacteria is an essential compartment that constitutes a
protective and permeability barrier between the cell and its environment. The envelope also …

The tubulin ancester, FtsZ, draughtsman, designer and driving force for bacterial cytokinesis

SG Addinall, B Holland - Journal of molecular biology, 2002 - Elsevier
We discuss in this review the regulation of synthesis and action of FtsZ, its structure in
relation to tubulin and microtubules, and the mechanism of polymerization and disassembly …