Abstract The interleukin-10 (IL-10) family of cytokines consists of six immune mediators,
namely IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. IL-10, IL-22, IL-24 and IL-26 are critical for …

Mycobacterium avium complex (MAC) is the main causative agent of infectious diseases in
humans among nontuberculous mycobacteria (NTM) that are ubiquitous organisms found in …

Mycobacterium tuberculosis is an intracellular pathogen of macrophages and escapes the
macrophages' bactericidal effectors by interfering with phagosome-lysosome fusion. IFN-γ …

Macrophages are key type of antigen-presenting cells that arbitrate the first line of defense
against various intracellular pathogens. Tuberculosis, both pulmonary and extrapulmonary …

Apoptotic and inflammatory pathways play important roles in Mycobacterium tuberculosis-
infected macrophages. Sirt1 is a member of the deacetylase family that is known to promote …

Tuberculosis is one of the leading causes of death by Mycobacterium tuberculosis (Mtb)
affecting millions of people worldwide. Mycobacterium species enter host macrophages …

Salmonella invasion protein A (SipA) is a dual-function effector protein that plays roles in
both actin polymerization and caspase-3 activation in intestinal epithelial cells. To date its …

To identify the resistance phenotype against Mycobacterium bovis in cattle, we used a
bactericidal assay that has been considered a marker of this trait. Three of 24 cows (12.5%) …

The fate of infected macrophages is a critical aspect of immunity to mycobacteria. By
depriving the pathogen of its intracellular niche, apoptotic death of the infected macrophage …

Background Mycobacterium tuberculosis is a particularly aggressive microorganism and the
host's defense is based on the induction of cellular immunity, in which the creation of a …