Pluronic® triblock copolymer-based nanoformulations for cancer therapy: A 10-year overview

KC de Castro, JC Coco, ÉM Dos Santos… - Journal of Controlled …, 2023 - Elsevier
This paper provides a review of the literature on the use of Pluronic® triblock copolymers for
drug encapsulation over the last 10 years. A special focus is given to the progress of drug …

Advances in the therapeutic delivery and applications of functionalized Pluronics: A critical review

P Singla, S Garg, J McClements, O Jamieson… - Advances in Colloid and …, 2022 - Elsevier
Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …

Direct and reverse pluronic micelles: Design and characterization of promising drug delivery nanosystems

A Naharros-Molinero, MÁ Caballo-González… - Pharmaceutics, 2022 - mdpi.com
Pluronics are a family of amphiphilic block copolymers broadly explored in the
pharmaceutical field. Under certain conditions, Pluronics self-assemble in different …

Soluplus® polymeric nanomicelles improve solubility of BCS-class II drugs

R Pignatello, R Corsaro, A Bonaccorso… - Drug Delivery and …, 2022 - Springer
The issue of poor aqueous solubility is often a great hitch in the development of liquid
dosage forms for those drugs that the Biopharmaceutics Classification System (BCS) …

Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications

D Xu, Y Li, S Yin, F Huang - Chemical Society Reviews, 2024 - pubs.rsc.org
Owing to their capacity for dynamically linking two or more functional molecules,
supramolecular coordination complexes (SCCs), exemplified by two-dimensional (2D) …

[HTML][HTML] Controlled temperature-mediated curcumin release from magneto-thermal nanocarriers to kill bone tumors

A Khodaei, F Jahanmard, HRM Hosseini, R Bagheri… - Bioactive Materials, 2022 - Elsevier
Systemic chemotherapy has lost its position to treat cancer over the past years mainly due to
drug resistance, side effects, and limited survival ratio. Among a plethora of local drug …

Folate-targeted Pluronic-chitosan nanocapsules loaded with IR780 for near-infrared fluorescence imaging and photothermal-photodynamic therapy of ovarian cancer

M Potara, T Nagy-Simon, M Focsan, E Licarete… - Colloids and Surfaces B …, 2021 - Elsevier
Herein, we report the fabrication of a nanotherapeutic platform integrating near-infrared
(NIR) imaging with combined therapeutic potential through photodynamic (PDT) and …

Luminescence ratiometric nanothermometry regulated by tailoring annihilators of triplet–triplet annihilation upconversion nanomicelles

L Li, C Zhang, L Xu, C Ye, S Chen… - Angewandte Chemie …, 2021 - Wiley Online Library
Triplet–triplet annihilation (TTA) upconversion is a special non‐linear photophysical process
that converts low‐energy photons into high‐energy photons based on sensitizer/annihilator …

Pluronic F68 micelles as carriers for an anti-inflammatory drug: A rheological and scattering investigation

NA Di Spirito, N Grizzuti, V Lutz-Bueno, G Urciuoli… - Langmuir, 2024 - ACS Publications
Age-long ambition of medical scientists has always been advancement in healthcare and
therapeutic medicine. Biomedical research indeed claims paramount importance in …

Labrasol mediated enhanced solubilization of natural hydrophobic drugs in Pluronic micelles: Physicochemical and in vitro release studies

J Kaur, P Singla, I Kaur - Journal of Molecular Liquids, 2022 - Elsevier
In present work, the solubilization of two natural hydrophobic drugs Quercetin (QCT) and
Curcumin (CUR) has been systematically investigated in Pluronics (P84, F127, F68) and …