Untangling mucosal drug delivery: engineering, designing, and testing nanoparticles to overcome the mucus barrier

J Watchorn, AJ Clasky, G Prakash… - ACS Biomaterials …, 2022 - ACS Publications
Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …

Synthesis of polyethylene glycol diacrylate/acrylic acid nanoparticles as nanocarriers for the controlled delivery of doxorubicin to colorectal cancer cells

YY Myat, T Ngawhirunpat, T Rojanarata, P Opanasopit… - Pharmaceutics, 2022 - mdpi.com
Doxorubicin (Dox) is known for its potential to deliver desirable anticancer effects against
various types of cancer including colorectal cancer. However, the adverse effects are …

[HTML][HTML] Synthesis and Characterization of Thiolated Nanoparticles Based on Poly (Acrylic Acid) and Algal Cell Wall Biopolymers for the Delivery of the Receptor …

I García-Silva, S Farfán-Castro, S Rosales-Mendoza… - Pharmaceutics, 2024 - mdpi.com
The COVID-19 pandemic required great efforts to develop efficient vaccines in a short period
of time. However, innovative vaccines against SARS-CoV-2 virus are needed to achieve …

Investigating the Fundamental Molecular Interactions Responsible for Polymer Mucoadhesion

JD Watchorn - 2023 - search.proquest.com
Polymer-protein interactions are fundamental to the success of drug delivery vehicles, as
they dictate their biological fate. There are many examples of these protein-polymer …

Development of nano-based drug-delivering carriers for colorectal and breast cancer targeting

YY MYAT, YY Myat, P Patrojanasophon - 2023 - ithesis-ir.su.ac.th
This study aimed to develop three types of nanocarriers for targeted delivery of
chemotherapeutic drugs to colorectal and breast cancers: Polyethylene glycol …