Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

Ionic liquids (ILs), due to their inherent structural tunability, outstanding miscibility behavior,
and excellent electrochemical properties, have attracted significant research attention in the …

In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

Due to the structure of acylhydrazones both by the pharmacophore–CO–NH–N= group and
by the different substituents present in the molecules of compounds of this class, various …

Small-molecule kinase inhibitors are being continuously explored as new anticancer
therapeutics. Kinases are the phosphorylating enzymes which regulate numerous cellular …

Microtubule affinity-regulating kinase (MARK4) plays a key role in Alzheimer's disease (AD)
development as its overexpression is directly linked to increased tau phosphorylation …

Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …

Bacopa monnieri (Brahmi) is a well-known perennial, creeping herb of the Indian Ayurveda
system; it contains numerous bioactive phytoconstituents implicated in the therapeutic …

The serine/threonine protein kinases CDK2 and GSK-3β are key oncotargets in breast
cancer cell lines, therefore, in the present study three series of oxindole-benzofuran hybrids …

4-Phenyl-3-[2-(phenylamino) ethyl]-1 H-1, 2, 4-triazole-5 (4 H)-thione was used as a starting
compound for the synthesis of the corresponding 1, 2, 4-triazol-3-ylthioacetohydrazide …