Emerging evidence points to a critical role for the skeleton in several homeostatic processes,
including energy balance. The connection between fuel utilization and skeletal remodeling …

Adipose tissue is an endocrine organ able to produce a wide series of pleiotropic molecules,
defined “adipokines”. In addition to the regulation of food intake and energy metabolism …

Purpose The traditional belief that obesity is protective against osteoporosis has been
questioned. Recent epidemiologic studies show that body fat itself may be a risk factor for …

Osteoporosis is a serious social issue nowadays. Both the high morbidity and its common
complication osteoporotic fracture load a heavy burden on the whole society. The adipose …

Introduction 3. Search strategies 4. Obesity and bone 4.1. Clinical studies 4.2. Experimental
studies 4.3. Pathophysiology and the role of cytokines 5. Alcohol-related bone disorders 5.1 …

Background The association between leptin and bone mineral density (BMD) is
controversial because of conflicting findings from previous studies. Methods This meta …

The association of bone mineral density (BMD) with obesity and insulin resistance remains
unclear. This study aimed to explore these associations in Tunisian menopausal women …

Context: Recombinant leptin (metreleptin) treatment restores bone mineral density in women
with hypothalamic amenorrhea (HA), a condition characterized by hypoleptinemia, which …

Introduction The ongoing repercussions of the COVID-19 pandemic include potentially
deleterious impacts on bone health. Aim This research aimed to ascertain the effects of …

The optimal type of exercise that simultaneously decreases body weight and preserves
bone health in people with obesity is unknown. This parallel randomized trial aimed to …