Obesity phenotypes and cardiovascular risk: from pathophysiology to clinical management

A Preda, F Carbone, A Tirandi, F Montecucco… - Reviews in Endocrine …, 2023 - Springer
Obesity epidemic reached the dimensions of a real global health crisis with more than one
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …

Update on obesity, the obesity paradox, and obesity management in heart failure

PL Alebna, A Mehta, A Yehya, CJ Lavie… - Progress in …, 2024 - Elsevier
Obesity is a major public health challenge worldwide. It is costly, predisposes to many
cardiovascular (CV) diseases (CVD), is increasing at an alarming rate, and …

Prevalence of sarcopenia and its association with clinical outcomes in heart failure: An updated meta‐analysis and systematic review

R Chen, J Xu, Y Wang, B Jiang, X Xu, Y Lan… - Clinical …, 2023 - Wiley Online Library
Background Sarcopenia is thought to be strongly associated with heart failure, but meta‐
analyses with sufficient samples are still lacking to accurately address its clinical situation …

Sex differences in musculoskeletal injury and disease risks across the lifespan: Are there unique subsets of females at higher risk than males for these conditions at …

DA Hart - Frontiers in Physiology, 2023 - frontiersin.org
Sex differences have been reported for diseases of the musculoskeletal system (MSK) as
well as the risk for injuries to tissues of the MSK system. For females, some of these occur …

Revisiting the obesity paradox in heart failure: what is the best anthropometric index to gauge obesity?

R Sato, S von Haehling - European Heart Journal, 2023 - academic.oup.com
It has become a bit of cliché to say that obesity is one of the chief risk factors for the
development of heart failure (HF). 1 Even though this is certainly true, the situation appears …

Obesity and weight loss strategies for patients with heart failure

AR Vest, PR Schauer, JE Rodgers, E Sanderson… - Heart Failure, 2024 - jacc.org
Obesity is a common comorbidity among patients with heart failure with reduced ejection
fraction (HFrEF) or heart failure with preserved ejection fraction (HFpEF), with the strongest …

Impact of whole-body and skeletal muscle composition on peak oxygen uptake in heart failure: a systematic review and meta-analysis

V Schmid, SJ Foulkes, D Walesiak… - … Heart Journal Open, 2024 - academic.oup.com
Aims Heart failure (HF) has a major impact on exercise tolerance that may (in part) be due to
abnormalities in body and skeletal muscle composition. This systematic review and meta …

Reduced thoracic skeletal muscle size is associated with adverse outcomes in diabetes patients with heart failure and reduced ejection fraction: quantitative analysis …

K Shi, G Zhang, H Fu, XM Li, SQ Yu, R Shi… - Cardiovascular …, 2024 - Springer
Background Sarcopenia is frequently found in patients with heart failure with reduced
ejection fraction (HFrEF) and is associated with reduced exercise capacity, poor quality of …

The Effects of Obesity on the Inflammatory, Cardiovascular, and Neurobiological Responses to Exercise in Older Adults

BG Fico, A Maharaj, GS Pena, CJ Huang - Biology, 2023 - mdpi.com
Simple Summary Our growing aging population and increased prevalence of obesity have
become an emerging health problem as these conditions lead to the development of related …

Understanding the development of sarcopenic obesity

DC Gross, CR Cheever, JA Batsis - Expert Review of …, 2023 - Taylor & Francis
ABSTRACT Introduction Sarcopenic obesity (SarcO) is defined as the confluence of reduced
muscle mass and function and excess body fat. The scientific community is increasingly …