Sodium is an essential ion that plays a central role in many physiological processes
including the transmembrane electrochemical gradient and the maintenance of the body's …

Seven tesla magnetic resonance imaging (7T MRI) is known to offer a superior spatial
resolution and a signal-to-noise ratio relative to any other non-invasive imaging technique …

Sodium serves as one of the primary cations in the central nervous system, playing a crucial
role in maintaining normal brain function. In this study, we investigated alterations in sodium …

Phosphorus magnetic resonance spectroscopy (31 P-MRS) is applied for non-invasive
studies of neuroenergetic metabolism in neurodegenerative diseases. However, the findings …

Background Physical activity and fitness are major targets in Alzheimer's disease (AD)
preventive research. However, current research is heterogeneous and often disregards the …

In patients with Friedreich ataxia, structural MRI is typically used to detect abnormalities
primarily in the brainstem, cerebellum, and spinal cord. The aim of the present study was to …

Alzheimer's disease is defined by the presence of β-amyloid plaques and neurofibrillary tau
tangles potentially preceding clinical symptoms by many years. Previously only detectable …

Dementia is a burgeoning global problem. Novel magnetic resonance imaging (MRI) metrics
beyond volumetry may bring new insight and aid clinical trial evaluation of interventions …

The sortilin-related receptor 1 (SORL1) gene, encoding the cellular endosomal sorting-
related receptor with A-type repeats (SORLA), is now established as a causal gene for …

Abstract Background and Purpose Alzheimer's disease (AD) is characterized by cognitive
decline and mnestic deficits. The pathophysiology of AD is not fully understood, which …