The Brain Connectome and New Methods of Lesion Analysis Complex neurologic and
psychiatric syndromes cannot be understood on the basis of focal brain lesions. Functional …

For more than one century, brain processing was mainly thought in a localizationist
framework, in which one given function was underpinned by a discrete, isolated cortical …

Most individuals who experience aphasia after a stroke recover to some extent, with the
majority of gains taking place in the first year. The nature and time course of this recovery …

Background Patients with brain lesions provide a unique opportunity to understand the
functioning of the human mind. However, even when focal, brain lesions have local and …

Broca's area in the posterior half of the left inferior frontal gyrus has long been thought to be
critical for speech production. The current view is that long-term speech production outcome …

Cognitive Neuroscience of Language provides an up-to-date, wide-ranging, and
pedagogically practical survey of the most important developments in this exciting field. It …

Stroke-induced aphasia is associated with adverse effects on quality of life and the ability to
return to work. For patients and clinicians the possibility of relying on valid predictors of …

Stroke causes focal brain lesions that disrupt functional connectivity (FC), a measure of
activity synchronization, throughout distributed brain networks. It is often assumed that FC …

Current evidence strongly suggests that the arcuate fasciculus (AF) is critical for language,
from spontaneous speech and word retrieval to repetition and comprehension abilities …

Lesion to symptom mapping (LSM) is a crucial tool for understanding the causality of brain-
behavior relationships. The analyses are typically performed by applying statistical methods …