The Principle of Cortical Development and Evolution

Z Yang - Neuroscience bulletin, 2024 - Springer
Human's robust cognitive abilities, including creativity and language, are made possible, at
least in large part, by evolutionary changes made to the cerebral cortex. This paper reviews …

Spatial enhancer activation influences inhibitory neuron identity during mouse embryonic development

E Dvoretskova, MC Ho, V Kittke, F Neuhaus… - Nature …, 2024 - nature.com
The mammalian telencephalon contains distinct GABAergic projection neuron and
interneuron types, originating in the germinal zone of the embryonic basal ganglia. How …

High order expression dependencies finely resolve cryptic states and subtypes in single cell data

A Jansma, Y Yao, J Wolfe, L Del Debbio… - Molecular Systems …, 2025 - embopress.org
Single cells are typically typed by clustering into discrete locations in reduced dimensional
transcriptome space. Here we introduce Stator, a data-driven method that identifies cell …

[HTML][HTML] The SoxE factor Sox9 is selectively expressed in indirect pathway striatal projection neurons and regulates synaptogenesis

X Song, X Li, X Pan, H Yang, K Wang, T Yang… - Fundamental …, 2024 - Elsevier
Striatum, as the largest structure of the basal ganglia, serves as a center for information
transmission and is critical for motor function and reward perception. However, the genetic …

Spatial enhancer activation determines inhibitory neuron identity

E Dvoretskova, MC Ho, V Kittke, F Neuhaus, I Vitali… - bioRxiv, 2023 - biorxiv.org
The mammalian telencephalon contains a tremendous diversity of GABAergic projection
neuron and interneuron types, that originate in a germinal zone of the embryonic basal …

In vivo and in vitro approaches to characterising axon growth and metabolic alterations in Parkinson's disease

M Travaglio - 2023 - repository.cam.ac.uk
A recent pathological hypothesis of Parkinson's disease suggests that at the time of disease
onset, midbrain dopaminergic cells lose their synaptic connectivity before dying. The …

Déficits développementaux du circuit striatal chez des modèles murins de la maladie de Huntington

M Lebouc - 2023 - theses.hal.science
La maladie de Huntington (MH) est une maladie neurodégénérative héréditaire causée par
une mutation sur le gène Huntingtine (Htt). Bien que les symptômes, caractérisés …