A brief history of bird flu

SJ Lycett, F Duchatel, P Digard - … Transactions of the …, 2019 - royalsocietypublishing.org
In 1918, a strain of influenza A virus caused a human pandemic resulting in the deaths of 50
million people. A century later, with the advent of sequencing technology and corresponding …

A year of terror and a century of reflection: perspectives on the great influenza pandemic of 1918–1919

ME Nickol, J Kindrachuk - BMC infectious diseases, 2019 - Springer
Background In the spring of 1918, the “War to End All Wars”, which would ultimately claim
more than 37 million lives, had entered into its final year and would change the global …

A novel bat coronavirus closely related to SARS-CoV-2 contains natural insertions at the S1/S2 cleavage site of the spike protein

H Zhou, X Chen, T Hu, J Li, H Song, Y Liu, P Wang… - Current biology, 2020 - cell.com
The unprecedented pandemic of pneumonia caused by a novel coronavirus, SARS-CoV-2,
in China and beyond has had major public health impacts on a global scale [1, 2]. Although …

The phylogenomics of evolving virus virulence

JL Geoghegan, EC Holmes - Nature Reviews Genetics, 2018 - nature.com
How virulence evolves after a virus jumps to a new host species is central to disease
emergence. Our current understanding of virulence evolution is based on insights drawn …

High pathogenicity avian influenza (H5N1) in Northern Gannets (Morus bassanus): Global spread, clinical signs and demographic consequences

JV Lane, JWE Jeglinski, S Avery‐Gomm, E Ballstaedt… - Ibis, 2024 - Wiley Online Library
During 2021 and 2022 High Pathogenicity Avian Influenza (HPAI) killed thousands of wild
birds across Europe and North America, suggesting a change in infection dynamics and a …

Geographical and historical patterns in the emergences of novel highly pathogenic avian influenza (HPAI) H5 and H7 viruses in poultry

MS Dhingra, J Artois, S Dellicour, P Lemey… - Frontiers in veterinary …, 2018 - frontiersin.org
Over the years, the emergence of novel H5 and H7 highly pathogenic avian influenza
viruses (HPAI) has been taking place through two main mechanisms: first, the conversion of …

Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients

JF Standing, L Buggiotti, JA Guerra-Assuncao… - Nature …, 2024 - nature.com
Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been
elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 …

A Genome-Wide Analysis of Promoter-Mediated Phenotypic Noise in Escherichia coli

OK Silander, N Nikolic, A Zaslaver, A Bren, I Kikoin… - PLoS …, 2012 - journals.plos.org
Gene expression is subject to random perturbations that lead to fluctuations in the rate of
protein production. As a consequence, for any given protein, genetically identical organisms …

Income disparities and the global distribution of intensively farmed chicken and pigs

M Gilbert, G Conchedda, TP Van Boeckel, G Cinardi… - PLoS …, 2015 - journals.plos.org
The rapid transformation of the livestock sector in recent decades brought concerns on its
impact on greenhouse gas emissions, disruptions to nitrogen and phosphorous cycles and …

The receptor binding domain of SARS-CoV-2 spike protein is the result of an ancestral recombination between the bat-CoV RaTG13 and the pangolin-CoV MP789

A Flores-Alanis, L Sandner-Miranda, G Delgado… - BMC research …, 2020 - Springer
Abstract Objective In December 2019 a novel coronavirus (SARS-CoV-2) that is causing the
current COVID-19 pandemic was identified in Wuhan, China. Many questions have been …