Small extracellular vesicles (SEVs) are extracellular vesicles containing DNA, RNA, and
proteins and are involved in intercellular communication and function, playing an essential …

Brain drug delivery is one of the most important bottlenecks in the development of drugs for
the central nervous system. Cumulative evidence has emerged that extracellular vesicles …

Background As a common joint disease, osteoarthritis (OA) is the main cause of limited joint
mobility and disability. The role of lncRNAs in the regulation of OA is increasingly …

Cellular composition and molecular signatures of the glioma core compared with infiltrative
margins are different, and it is well known that the tumor edge is enriched in microglia. In this …

Exosomes, the small extracellular vesicles, are released by multiple cell types, including
tumor cells, and represent a novel avenue for intercellular communication via transferring …

MicroRNAs (miRNAs) are transcripts with sizes of about 22 nucleotides, which are produced
through a multistep process in the nucleus and cytoplasm. These transcripts modulate the …

A wide array of different factors and processes have been linked to the biochemical
underpinnings of glioblastoma multiforme (GBM) and glioblastoma stem cells (GSC), with no …

Astrocytes are highly plastic cells whose activity is essential to maintain the cerebral
homeostasis, regulating synaptogenesis and synaptic transmission, vascular and metabolic …

Glioblastoma multiforme is the most common, highly aggressive malignant brain tumor
which is marked by highest inter-and intra-tumoral heterogeneity. Despite, immunotherapy …

Glioma stem cell (GSC)–derived extracellular vesicles (EVs) can mediate the
communication between GSCs and microglia. Metastasis-associated lung adenocarcinoma …