Obesity has tripled over the past 40 years to become a major public health issue, as it is
linked with increased mortality and elevated risk for various physical and neuropsychiatric …

Accumulated preclinical literature demonstrates that hypothalamic inflammation and gliosis
are underlying causal components of diet-induced obesity in rodent models. This review …

Despite the crucial role of the hypothalamus in the regulation of the human body,
neuroimaging studies of this structure and its nuclei are scarce. Such scarcity partially stems …

International Journal of Epidemiology, 2023, e66–e79 https://doi. org/10.1093/ije/dyac114
Advance Access Publication Date: 28 May 2022 Cohort Profile comprehensive molecular …

Schizophrenia is a severe psychiatric disorder affecting 21 million people worldwide. People
with schizophrenia suffer from symptoms including psychosis and delusions, apathy …

Obesity and its comorbidities are long-standing, challenging global health problems. Lack of
exercise, overnutrition, and especially the consumption of fat-rich foods are some of the most …

Neurodegeneration of the central and enteric nervous systems is a common feature of aging
and aging-related diseases, and is accelerated in individuals with metabolic dysfunction …

Noise in gene expression is one of the hallmarks of life at the molecular scale. Here we
derive analytical solutions to a set of models describing the molecular mechanisms …

Numerous studies have shown that microglia are capable of producing a wide range of
chemokines to promote inflammatory processes within the central nervous system (CNS) …

Hypothalamus (HT), this small structure often perceived through the prism of neuroimaging
as morphologically and functionally homogeneous, plays a key role in the primitive act of …